NP_058705.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,782 Da
NCBI Official Full Name
glial fibrillary acidic protein
NCBI Official Synonym Full Names
glial fibrillary acidic protein
NCBI Protein Information
glial fibrillary acidic protein; glial fibrillary acidic protein alpha; intermediate filament
UniProt Protein Name
Glial fibrillary acidic protein
UniProt Synonym Gene Names
UniProt Entry Name
GFAP_RAT
NCBI Summary for GFAP
intermediate filament protein specific for astrocytes [RGD, Feb 2006]
UniProt Comments for GFAP
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined.
Protein type: Cytoskeletal
Cellular Component: cell projection; membrane; cytoplasm; intermediate filament; myelin sheath
Molecular Function: integrin binding; structural constituent of cytoskeleton; structural molecule activity; kinase binding
Biological Process: Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; regulation of neurotransmitter uptake; response to wounding; neurite regeneration; intermediate filament organization; intermediate filament-based process; astrocyte development
Research Articles on GFAP
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Pathways associated with anti-GFAP antibody
Diseases associated with anti-GFAP antibody
Organs/Tissues associated with anti-GFAP antibody
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