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anti-GM-CSF antibody :: Mouse anti-Human GM-CSF Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS335044 anti-GM-CSF antibody
Unit / Price
0.2 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GM-CSF, Monoclonal Antibody

 Also Known As   

Mouse Anti-Human GM-CSF Monoclonal Antibody, Azide Free Clone B-Z13

 Product Synonym Names    GM-CSF
 Product Gene Name   

anti-GM-CSF antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138960
 3D Structure    ModBase 3D Structure for P04141
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    B-Z13
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Recognises recombinant and natural GM-CSF (Granulocytemacrophage colony-stimulating factor)
 Purity/Purification    Ion exchange chromatography
 Form/Format    Azide free
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
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 Antigen    GM-CSF
 Hybridoma    Myeloma X63/AG.8653 x Balb/c node cells
 Immunisation    Recombinant human GM-CSF
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 Preparation and Storage    Store at +2-8 degree C for 12 months. DO NOT FREEZE.
 Other Notes    Small volumes of anti-GM-CSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GM-CSF antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for GM-CSF. It may not necessarily be applicable to this product.
 NCBI GI #    183364
 NCBI GeneID    1437
 NCBI Accession #    AAA52578.1 [Other Products]
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 UniProt Primary Accession #    P04141 [Other Products]
 UniProt Secondary Accession #    Q14CE8; Q2VPI8; Q8NFI6 [Other Products]
 UniProt Related Accession #    P04141 [Other Products]
 Molecular Weight    16,295 Da
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 NCBI Official Full Name    GM-CSF
 NCBI Official Synonym Full Names    colony stimulating factor 2 (granulocyte-macrophage)
 NCBI Official Symbol    CSF2 [Similar Products]
 NCBI Official Synonym Symbols   
GMCSF
[Similar Products]
 NCBI Protein Information    granulocyte-macrophage colony-stimulating factor
 UniProt Protein Name    Granulocyte-macrophage colony-stimulating factor
 UniProt Synonym Protein Names   
Colony-stimulating factor; CSF; Molgramostin; Sargramostim
 UniProt Gene Name    CSF2 [Similar Products]
 UniProt Synonym Gene Names    GMCSF; GM-CSF; CSF [Similar Products]
 UniProt Entry Name    CSF2_HUMAN
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 NCBI Summary for GM-CSF    The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GM-CSF    GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; growth factor activity; granulocyte macrophage colony-stimulating factor receptor binding; cytokine activity

Biological Process: negative regulation of cytolysis; epithelial fluid transport; embryonic placenta development; macrophage activation; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of interleukin-23 production; positive regulation of cell proliferation; myeloid dendritic cell differentiation; immune response; positive regulation of DNA replication
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 Research Articles on GM-CSF    1. Influenza infection stimulates the secretion of IL-8 and GM-CSF by alveolar epithelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Mouse Anti-Human GM-CSF Monoclonal Antibody, Azide Free Clone B-Z13
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 MBS8244636  Mouse GM-CSF ELISA Kit  MBS844430  GM-CSF, murine recombinant
 MBS691828  Mouse GM-CSF  MBS695698  Animal Free Rat GM-CSF
 MBS592138  mAb anti-human GM-CSF  MBS266857  Human Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) ELISA Kit
 MBS692145  Rat GM-CSF  MBS2507633  Rat GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) ELISA Kit
 MBS355602  GM-CSF Protein (Active)  MBS220198  RABBIT ANTI HUMAN GM-CSF:Biotin
Products associated with anti-GM-CSF antibodyPathways associated with anti-GM-CSF antibody
 Reference Product  PubMed Publications
 IL4 antibody  >19 publications with GM-CSF and IL4
 IL3 antibody  >14 publications with GM-CSF and IL3
 IL2 antibody  >11 publications with GM-CSF and IL2
 CSF2RB antibody  >10 publications with GM-CSF and CSF2RB
 CSF2RA antibody  >5 publications with GM-CSF and CSF2RA
 FOS antibody  >3 publications with GM-CSF and FOS
 JAK2 antibody  >3 publications with GM-CSF and JAK2
 SDC2 antibody  >1 publications with GM-CSF and SDC2
 STAT5B antibody  >1 publications with GM-CSF and STAT5B
 STAT5A antibody  >1 publications with GM-CSF and STAT5A
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
Diseases associated with anti-GM-CSF antibodyOrgans/Tissues associated with anti-GM-CSF antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >44 publications with GM-CSF and Inflammation
 Necrosis Antibodies  >28 publications with GM-CSF and Necrosis
 Lung Diseases Antibodies  >10 publications with GM-CSF and Lung Diseases
 Breast Neoplasms Antibodies  >7 publications with GM-CSF and Breast Neoplasms
 Carcinoma Antibodies  >5 publications with GM-CSF and Carcinoma
 Neoplasms, Experimental Antibodies  >4 publications with GM-CSF and Neoplasms, Experimental
 Leukemia, Myeloid, Acute Antibodies  >3 publications with GM-CSF and Leukemia, Myeloid, Acute
 Arthritis, Rheumatoid Antibodies  >3 publications with GM-CSF and Arthritis, Rheumatoid
 Anemia Antibodies  >3 publications with GM-CSF and Anemia
 Lung Neoplasms Antibodies  >3 publications with GM-CSF and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with GM-CSF and Blood
 Bone Antibodies  >18 publications with GM-CSF and Bone
 Lung Antibodies  >17 publications with GM-CSF and Lung
 Intestine Antibodies  >3 publications with GM-CSF and Intestine
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