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anti-GPX3 antibody :: Mouse anti-Human Glutathione Peroxidase 3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS834494
Western Blot (WB)
Unit / Price
0.1 mL  /  $395 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glutathione Peroxidase 3 (GPX3), Monoclonal Antibody

 Also Known As   

Glutathione Peroxidase 3 antibody

 Product Synonym Names    Monoclonal Glutathione Peroxidase 3; Anti-Glutathione Peroxidase 3; GPX3; glutathione peroxidase 3 (plasma); BOS_8292; EGPx; extracellular glutathione peroxidase; extracellular GPx; glutathione peroxidase 3; GPx; GPx-3; Gpxp; GPx-P; GSHPx-3; GSHPx-P; plasma glutathione peroxidase; plasma GPx
 Product Gene Name   

anti-GPX3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138321
 3D Structure    ModBase 3D Structure for P22352
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 Clonality    Monoclonal
 Isotype    IgG2b kappa
 Clone Number    55A
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Glutathione Peroxidase 3 antibody was purified by ammonium sulfate precipitation
 Form/Format    Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
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 Biological Significance    Glutathione Peroxidase 3 (GPX3), also known as Plasma Glutathione Peroxidase, is a 226 amino acid member of the glutathione peroxidase antioxidant enzyme family. The Glutathione Peroxidase family protects cell surfaces, extracellular fluid components, and enzymes from oxidative stress by catalysing the reduction of hydrogen peroxide, lipid peroxides, and organic hydroperoxide using reduced glutathione.
 Immunogen    Glutathione Peroxidase 3 antibody was raised in Mouse using a recombinant human protein purified from E Coli as the immunogen
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 Preparation and Storage    Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
 Other Notes    Small volumes of anti-GPX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-GPX3 antibody

   Mouse monoclonal Glutathione Peroxidase 3 antibody
 Product Categories/Family for anti-GPX3 antibody    Signal Transduction
 Applications Tested/Suitable for anti-GPX3 antibody   

ELISA (EIA), Immunoprecipitation (IP)

 Application Notes for anti-GPX3 antibody    IP: 1 ul
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 Western Blot (WB) of anti-GPX3 antibody   
anti-GPX3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GPX3. It may not necessarily be applicable to this product.
 NCBI GI #    6006001
 NCBI GeneID    2878
 NCBI Accession #    NP_002075.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002084.3 [Other Products]
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 UniProt Primary Accession #    P22352 [Other Products]
 UniProt Secondary Accession #    O43787; Q86W78; Q9NZ74; Q9UEL1 [Other Products]
 UniProt Related Accession #    P22352 [Other Products]
 Molecular Weight    25,552 Da [Similar Products]
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 NCBI Official Full Name    glutathione peroxidase 3
 NCBI Official Synonym Full Names    glutathione peroxidase 3
 NCBI Official Symbol    GPX3 [Similar Products]
 NCBI Official Synonym Symbols   
GPx-P; GSHPx-3; GSHPx-P
[Similar Products]
 NCBI Protein Information    glutathione peroxidase 3
 UniProt Protein Name    Glutathione peroxidase 3
 UniProt Synonym Protein Names   
Extracellular glutathione peroxidase; Plasma glutathione peroxidase; GPx-P; GSHPx-P
 Protein Family    Glutathione peroxidase
 UniProt Gene Name    GPX3 [Similar Products]
 UniProt Synonym Gene Names    GPXP; GPx-3; GSHPx-3; GPx-P; GSHPx-P [Similar Products]
 UniProt Entry Name    GPX3_HUMAN
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 NCBI Summary for GPX3    This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GPX3    GPX3: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. Belongs to the glutathione peroxidase family.

Protein type: Other Amino Acids Metabolism - glutathione; Lipid Metabolism - arachidonic acid; EC 1.11.1.9; Secreted, signal peptide; Secreted; Oxidoreductase

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: extracellular space; extracellular region

Molecular Function: selenium binding; glutathione peroxidase activity; transcription factor binding

Biological Process: response to reactive oxygen species; response to lipid hydroperoxide; hydrogen peroxide catabolic process; protein homotetramerization
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 Research Articles on GPX3    1. Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's esophagus: results from biomarkers and genetic variants.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GPX3 antibodyPathways associated with anti-GPX3 antibody
 Reference Product  PubMed Publications
 SOD3 antibody  >10 publications with GPX3 and SOD3
 GSTP1 antibody  >7 publications with GPX3 and GSTP1
 TNF antibody  >6 publications with GPX3 and TNF
 GSTM3 antibody  >4 publications with GPX3 and GSTM3
 GSTO1 antibody  >2 publications with GPX3 and GSTO1
 GSTO2 antibody  >1 publications with GPX3 and GSTO2
 GSTT1 antibody  >1 publications with GPX3 and GSTT1
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Oxidative Stress Pathway antibodies  Oxidative Stress Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram
Diseases associated with anti-GPX3 antibodyOrgans/Tissues associated with anti-GPX3 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >27 publications with GPX3 and Cardiovascular Diseases
 Inflammation Antibodies  >24 publications with GPX3 and Inflammation
 Disease Models, Animal Antibodies  >20 publications with GPX3 and Disease Models, Animal
 Death Antibodies  >18 publications with GPX3 and Death
 Necrosis Antibodies  >16 publications with GPX3 and Necrosis
 Adenocarcinoma Antibodies  >14 publications with GPX3 and Adenocarcinoma
 Prostatic Neoplasms Antibodies  >13 publications with GPX3 and Prostatic Neoplasms
 Obesity Antibodies  >11 publications with GPX3 and Obesity
 Insulin Resistance Antibodies  >9 publications with GPX3 and Insulin Resistance
 Kidney Diseases Antibodies  >8 publications with GPX3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >94 publications with GPX3 and Blood
 Liver Antibodies  >41 publications with GPX3 and Liver
 Kidney Antibodies  >30 publications with GPX3 and Kidney
 Muscle Antibodies  >26 publications with GPX3 and Muscle
 Lung Antibodies  >20 publications with GPX3 and Lung
 Thyroid Antibodies  >18 publications with GPX3 and Thyroid
 Prostate Antibodies  >17 publications with GPX3 and Prostate
 Heart Antibodies  >16 publications with GPX3 and Heart
 Brain Antibodies  >12 publications with GPX3 and Brain
 Adipose Tissue Antibodies  >11 publications with GPX3 and Adipose Tissue
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