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anti-GYPC antibody :: Mouse Glycophorin C Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS632910 anti-GYPC antibody
Unit / Price
0.2 mg  /  $975 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glycophorin C (GYPC), Monoclonal Antibody

 Also Known As   

Glycophorin C (Glycophorin-C, Glycoconnectin, Glycophorin-D, GPD, Glycoprotein beta, PAS-2', Sialoglycoprotein D, CD236, GYPC, GLPC, GPC)

 Product Synonym Names    Anti -Glycophorin C (Glycophorin-C, Glycoconnectin, Glycophorin-D, GPD, Glycoprotein beta, PAS-2', Sialoglycoprotein D, CD236, GYPC, GLPC, GPC)
 Product Gene Name   

anti-GYPC antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (127413426..127454251). Location: 2q14-q21
 OMIM    110750
 3D Structure    ModBase 3D Structure for P04921
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    BRIC100
 Host    Mouse
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 Specificity    Recognizes human CD236a.
 Purity/Purification    Purified
 Form/Format    Supplied as a liquid in Tris buffered glycine, pH7.5, 0.09% sodium azide.
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 Immunogen    Synthetic peptide corresponding to amino acids in the cytoplasmic domain of GPC.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-GYPC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GYPC antibody

   Four main species of sialic acid-rich glycoproteins known as glycophorins A, B, C, and D have been characterized on human erythrocytes. These components carry blood group determinants and various receptors for lectins, bacteria, viruses, and parasites. Glycophorin C (GPC) is the minor constituent carrying the Gerbich blood group antigens which plays significant role in the maintenance of erythrocyte shape by regulating the deformability and mechanical stability of red cells. The protein is a single polypeptide chain of 128aa spanning the phospholipid bilayer. The gene encoding for glycophorin C is mapped on 2q14-q21 region of human chromosome organized in four exons over 13.5kb pair DNA and contains two internal direct repeated domains of 3.4kb which are likely to derive from a recent duplication. Glycophorin C has very little homology with glycophorin A and B.
 Product Categories/Family for anti-GYPC antibody    Antibodies; Abs to CD Markers
 Applications Tested/Suitable for anti-GYPC antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

 Application Notes for anti-GYPC antibody    Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry.
Dilution: Immunohistochemistry: frozen
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NCBI/Uniprot data below describe general gene information for GYPC. It may not necessarily be applicable to this product.
 NCBI GI #    1617086
 NCBI GeneID    2995
 NCBI Accession #    CAA32093.1 [Other Products]
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 UniProt Primary Accession #    P04921 [Other Products]
 UniProt Secondary Accession #    Q53SV9; Q92642; B2R522 [Other Products]
 UniProt Related Accession #    P04921 [Other Products]
 Molecular Weight    13,811 Da [Similar Products]
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 NCBI Official Full Name    glycophorin C
 NCBI Official Synonym Full Names    glycophorin C (Gerbich blood group)
 NCBI Official Symbol    GYPC [Similar Products]
 NCBI Official Synonym Symbols   
GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2'
[Similar Products]
 NCBI Protein Information    glycophorin-C; glycophorin-D; glycoconnectin; glycoprotein beta; sialoglycoprotein D
 UniProt Protein Name    Glycophorin-C
 UniProt Synonym Protein Names   
Glycoconnectin; Glycophorin-D; GPD; Glycoprotein beta; PAS-2'; Sialoglycoprotein D
 Protein Family    Glycophorin
 UniProt Gene Name    GYPC [Similar Products]
 UniProt Synonym Gene Names    GLPC; GPC; GPD [Similar Products]
 UniProt Entry Name    GLPC_HUMAN
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 NCBI Summary for GYPC    Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
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 UniProt Comments for GYPC    GYPC: This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. Belongs to the glycophorin-C family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q14-q21

Cellular Component: cortical cytoskeleton; membrane; integral to plasma membrane; plasma membrane

Molecular Function: protein binding

Disease: Malaria, Susceptibility To; Blood Group, Gerbich System
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 Research Articles on GYPC    1. Glycophorin C delta (exon3) is not associated with protection against severe anaemia in Papua New Guinea.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-GYPC antibodyDiseases associated with anti-GYPC antibody
 Products by Pathway  Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Disease Name  Pubmed Publications
 Malaria Antibodies  >6 publications with GYPC and Malaria
 Anemia, Hemolytic Antibodies  >1 publications with GYPC and Anemia, Hemolytic
 Neoplasms Antibodies  >1 publications with GYPC and Neoplasms
Organs/Tissues associated with anti-GYPC antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >19 publications with GYPC and Blood
 Brain Antibodies  >2 publications with GYPC and Brain
 Bone Marrow Antibodies  >1 publications with GYPC and Bone Marrow
 Embryonic Tissue Antibodies  >1 publications with GYPC and Embryonic Tissue
 Bone Antibodies  >1 publications with GYPC and Bone
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