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anti-GCSF antibody :: Granylocyte colony stimulating factor Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS660033 anti-GCSF antibody
Unit / Price
1 mg  /  $660 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Granylocyte colony stimulating factor (GCSF), Monoclonal Antibody

 Also Known As   

Monoclonal mouse anti-Human Granulocyte Colony Stimulating Factor (GCSF)

 Product Gene Name   

anti-GCSF antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138970
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 Clonality    Monoclonal
 Isotype    IgG1 for MAbs GSB2, GSB3
IgG2a for MAb GSF12
IgG2b for MAbs CF-C8, CF-A1, GSA1
 Clone Number    CF-C8, CF-A1; New MAbs: GSA1, GSB2, GSB3, GSF12
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 Specificity    Human Granuldegree Cyte Colony Stimulating Factor (GCSF)
 Purity/Purification    Chromatography on protein G Sepharose
 Form/Format    PBS, pH 7.2, 0.1 % sodium azide (NaN3)
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 Clone Note    Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with recombinant GCSF.
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 Preparation and Storage    4 degree C
 Other Notes    Small volumes of anti-GCSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Application Notes for anti-GCSF antibody    MAbs are working in ELISA.
Recommended pair for sandwich immunoassay are (capture - detection): GSB2 - GSB3, GSB2 - GSF12, GSF12 - GSA1, CF-C8 - CF-A1.
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NCBI/Uniprot data below describe general gene information for GCSF. It may not necessarily be applicable to this product.
 NCBI GI #    296011057
 NCBI GeneID    1440
 NCBI Accession #    NP_001171618.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001178147.1 [Other Products]
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 UniProt Secondary Accession #    A8MXR7 [Other Products]
 UniProt Related Accession #    P09919 [Other Products]
 Molecular Weight    18,434 Da
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 NCBI Official Full Name    granulocyte colony-stimulating factor isoform d
 NCBI Official Synonym Full Names    colony stimulating factor 3 (granulocyte)
 NCBI Official Symbol    CSF3 [Similar Products]
 NCBI Official Synonym Symbols   
GCSF; CSF3OS; C17orf33
[Similar Products]
 NCBI Protein Information    granulocyte colony-stimulating factor; filgrastim; lenograstim; pluripoietin; granulocyte-colony stimulating factor
 UniProt Protein Name    Granulocyte colony-stimulating factor
 UniProt Synonym Protein Names   
Pluripoietin; INN: Filgrastim; INN: Lenograstim
 UniProt Gene Name    CSF3 [Similar Products]
 UniProt Synonym Gene Names    C17orf33; GCSF; G-CSF [Similar Products]
 UniProt Entry Name    CSF3_HUMAN
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 NCBI Summary for GCSF    The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
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 UniProt Comments for GCSF    G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space

Molecular Function: enzyme binding; growth factor activity; cytokine activity; granulocyte colony-stimulating factor receptor binding

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of myeloid cell differentiation; positive regulation of actin filament polymerization; positive regulation of protein binding; granulocyte differentiation; multicellular organismal development; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation
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 Research Articles on GCSF    1. Data suggest that long-term protein secondary structural stability/unfolding of GCSF can be modeled from short-term physicochemical phenomena assessed via spectroscopic measurements.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GCSF antibodyPathways associated with anti-GCSF antibody
 Reference Product  PubMed Publications
 CSF3R antibody  >14 publications with GCSF and CSF3R
 MMP9 antibody  >7 publications with GCSF and MMP9
 IL10 antibody  >6 publications with GCSF and IL10
 CXCL12 antibody  >3 publications with GCSF and CXCL12
 ERBB2 antibody  >2 publications with GCSF and ERBB2
 STAT3 antibody  >2 publications with GCSF and STAT3
 SELL antibody  >1 publications with GCSF and SELL
 CXCR4 antibody  >1 publications with GCSF and CXCR4
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
Diseases associated with anti-GCSF antibodyOrgans/Tissues associated with anti-GCSF antibody
 Disease Name  Pubmed Publications
 Disease Susceptibility Antibodies  >6 publications with GCSF and Disease Susceptibility
 Nervous System Diseases Antibodies  >5 publications with GCSF and Nervous System Diseases
 Breast Neoplasms Antibodies  >3 publications with GCSF and Breast Neoplasms
 Neutropenia Antibodies  >3 publications with GCSF and Neutropenia
 Leukopenia Antibodies  >2 publications with GCSF and Leukopenia
 Anemia Antibodies  >2 publications with GCSF and Anemia
 Neoplasm Metastasis Antibodies  >2 publications with GCSF and Neoplasm Metastasis
 Leukemia, Myeloid, Acute Antibodies  >2 publications with GCSF and Leukemia, Myeloid, Acute
 Peripheral Nervous System Diseases Antibodies  >1 publications with GCSF and Peripheral Nervous System Diseases
 Pulmonary Fibrosis Antibodies  >1 publications with GCSF and Pulmonary Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >7 publications with GCSF and Skin
 Lung Antibodies  >5 publications with GCSF and Lung
 Muscle Antibodies  >4 publications with GCSF and Muscle
 Brain Antibodies  >3 publications with GCSF and Brain
 Liver Antibodies  >2 publications with GCSF and Liver
 Uterus Antibodies  >2 publications with GCSF and Uterus
 Uncharacterized Tissue Antibodies  >1 publications with GCSF and Uncharacterized Tissue
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