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anti-hcn1 antibody :: Mouse HCN1 Cyclic nucleotide-gated Channel Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS190535 anti-hcn1 antibody
Unit / Price
0.1 mg  /  $390 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HCN1 Cyclic nucleotide-gated Channel, Monoclonal Antibody

 Also Known As   

Anti-HCN1 Cyclic Nucleotide-Gated Channel Monoclonal Antibody

 Product Gene Name   

anti-hcn1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    778-910
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 Clonality    Monoclonal
 Isotype    lgG1
 Clone Number    S70-28
 Host    Mouse
 Species Reactivity    Human, mouse, rat
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 Specificity    HCN1 Cyclic nucleotide-gated Channel
This antibody recognizes human, mouse, and rat HCN1. It does not cross-react with HCN2.
 Form/Format    100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography
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 Antigen    Fusion protein aa 778-910 (C-terminus) of rat HCN! (accession number Q9JKBO).
 Dilution Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-hcn1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-hcn1 antibody

   Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulation of cell excitability. They contribute to spontaneous rhythmic activity in the heart and brain.
 Applications Tested/Suitable for anti-hcn1 antibody   

Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence

 Application Notes for anti-hcn1 antibody    Immunoblotting: use at 1-10ug/ml. A band of ~100kDa is detected. Immunohistochemistry and Immunocytochemistry: use at 0.1-1 ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate
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NCBI/Uniprot data below describe general gene information for hcn1. It may not necessarily be applicable to this product.
 NCBI GI #    185136002
 NCBI GeneID    100135980
 NCBI Accession #    NP_001117790.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001124318.1 [Other Products]
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 NCBI Official Full Name    hyperpolarization-activated cyclic nucleotide-gated cation channel 1
 NCBI Official Symbol    hcn1 [Similar Products]
 NCBI Protein Information    hyperpolarization-activated cyclic nucleotide-gated cation channel 1
 Protein Family    Anaphase-promoting complex
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-hcn1 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with hcn1 and Bone
 Connective Tissue Antibodies  >4 publications with hcn1 and Connective Tissue
 Heart Antibodies  >3 publications with hcn1 and Heart
 Muscle Antibodies  >3 publications with hcn1 and Muscle
 Brain Antibodies  >3 publications with hcn1 and Brain
 Vascular Antibodies  >2 publications with hcn1 and Vascular
 Embryonic Tissue Antibodies  >2 publications with hcn1 and Embryonic Tissue
 Ear Antibodies  >1 publications with hcn1 and Ear
 Kidney Antibodies  >1 publications with hcn1 and Kidney
 Umbilical Cord Antibodies  >1 publications with hcn1 and Umbilical Cord
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