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anti-HCN3 antibody :: Mouse anti-Mouse, rat HCN3 Cyclic nucleotide-gated Channel Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS190602 anti-HCN3 antibody
Unit / Price
0.1 mg  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HCN3 Cyclic nucleotide-gated Channel, Monoclonal Antibody

 Also Known As   

Anti-HCN3 Cyclic Nucleotide-Gated Channel Monoclonal Antibody

 Product Gene Name   

anti-HCN3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence Positions    660-779
 Chromosome Location    Chromosome: 3; NC_007301.4 (16749380..16758360, complement)
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 Clonality    Monoclonal
 Isotype    lgG1
 Clone Number    S141-28
 Host    Mouse
 Species Reactivity    Mouse, rat
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 Specificity    HCN3 Cyclic nucleotide-gated Channel
This antibody recognizes mouse and rat HCN3. It does not cross-react with other HCNs.
 Form/Format    100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
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 Antigen    Fusion protein aa 660-779 (cytoplasmic C-terminus) of mouse HCN3 (accession number O88705).
 Dilution Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-HCN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-HCN3 antibody

   Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Hyperpolarization-activated cation channels of the HCN gene family, such as HCN3, play a crucial role in the regulation of cell excitability. They contribute to spontaneous rhythmic activity in the heart and brain.
 Applications Tested/Suitable for anti-HCN3 antibody   

Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence

 Application Notes for anti-HCN3 antibody    Immunoblotting: use at 1-10ug/ml. A band of ~90kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate
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NCBI/Uniprot data below describe general gene information for HCN3. It may not necessarily be applicable to this product.
 NCBI GI #    296489729
 NCBI GeneID    539578
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 NCBI Official Full Name    hyperpolarization-activated, cyclic nucleotide-gated K+ 3-like
 NCBI Official Symbol    HCN3 [Similar Products]
 NCBI Protein Information    potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
 Protein Family    Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-HCN3 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with HCN3 and Bone
 Connective Tissue Antibodies  >4 publications with HCN3 and Connective Tissue
 Heart Antibodies  >3 publications with HCN3 and Heart
 Muscle Antibodies  >3 publications with HCN3 and Muscle
 Brain Antibodies  >3 publications with HCN3 and Brain
 Vascular Antibodies  >2 publications with HCN3 and Vascular
 Embryonic Tissue Antibodies  >2 publications with HCN3 and Embryonic Tissue
 Ear Antibodies  >1 publications with HCN3 and Ear
 Kidney Antibodies  >1 publications with HCN3 and Kidney
 Umbilical Cord Antibodies  >1 publications with HCN3 and Umbilical Cord
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