BC018991
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,264 Da
NCBI Official Full Name
Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like), mRNA
NCBI Official Synonym Full Names
hepatoma-derived growth factor
NCBI Official Synonym Symbols
NCBI Protein Information
hepatoma-derived growth factor; HMG-1L2; high mobility group protein 1-like 2
UniProt Protein Name
Hepatoma-derived growth factor
UniProt Synonym Protein Names
High mobility group protein 1-like 2; HMG-1L2
UniProt Entry Name
HDGF_HUMAN
NCBI Summary for HDGF
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for HDGF
HDGF: Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. Belongs to the HDGF family.
Protein type: Transcription regulation; Cytokine
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: nucleoplasm; extracellular space; transcriptional repressor complex; cytoplasm
Molecular Function: heparin binding; DNA binding; growth factor activity; nucleotide binding
Biological Process: cell proliferation; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; transcription, DNA-dependent; unfolded protein response; negative regulation of transcription from RNA polymerase II promoter; signal transduction
Research Articles on HDGF
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Products associated with anti-HDGF antibody
Pathways associated with anti-HDGF antibody
Diseases associated with anti-HDGF antibody
Organs/Tissues associated with anti-HDGF antibody
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