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anti-HDLBP antibody :: Mouse anti-Human HDLBP Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120346
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HDLBP, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human HDLBP

 Product Synonym Names    Homo sapiens high density lipoprotein binding protein (vigilin); HBP; VGL; PRO2900; FLJ16432
 Product Gene Name   

anti-HDLBP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    142695
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2404C3a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-HDLBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HDLBP antibody

   High density lipoprotein-binding protein, also known as vigilin, is a 110-kD protein that specifically binds HDL molecules and may function in the removal of excess cellular cholesterol.[supplied by OMIM] [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-HDLBP antibody   

Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

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 Quality Control of anti-HDLBP antibody    Western blot analysis of immunized recombinant protein, using anti-HDLBP monoclonal antibody.
anti-HDLBP antibody Quality Control image
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 Quality Control #2 of anti-HDLBP antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-HDLBP antibody Quality Control #2 image
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 Western Blot (WB) of anti-HDLBP antibody    Detection of HDLBP by Western blot.

Samples: Whole cell lysate from human HEK293 (H, 25 ug), mouse NIH3T3 (M, 25 ug) and rat F2408 (R, 25 ug) cells. [Lot No. 2404C3a-1]

Predicted molecular weight: 23 kDa
anti-HDLBP antibody Western Blot (WB) (WB) image
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 Immunocytochemistry (ICC) of anti-HDLBP antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-HDLBP mAb. [Lot No. 2404C3a-1]
anti-HDLBP antibody Immunocytochemistry (ICC) (ICC) image
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NCBI/Uniprot data below describe general gene information for HDLBP. It may not necessarily be applicable to this product.
 NCBI GI #    345199281
 NCBI GeneID    3069
 NCBI Accession #    NP_005327.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005336 [Other Products]
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 UniProt Secondary Accession #    Q53QU2; Q9UCY3; B4DTQ2; E7EM71 [Other Products]
 UniProt Related Accession #    Q00341 [Other Products]
 Molecular Weight    137,987 Da
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 NCBI Official Full Name    Homo sapiens high density lipoprotein binding protein (HDLBP), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    high density lipoprotein binding protein
 NCBI Official Symbol    HDLBP [Similar Products]
 NCBI Official Synonym Symbols   
HBP; VGL; PRO2900
[Similar Products]
 NCBI Protein Information    vigilin; HDL-binding protein; high density lipoprotein-binding protein
 UniProt Protein Name    Vigilin
 UniProt Synonym Protein Names   
High density lipoprotein-binding protein; HDL-binding protein
 Protein Family    Vigilin
 UniProt Gene Name    HDLBP [Similar Products]
 UniProt Entry Name    VIGLN_HUMAN
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 NCBI Summary for HDLBP    The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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 UniProt Comments for HDLBP    vigilin: a nuclear and cytoplasmic protein that may play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

Protein type: RNA-binding; Lipid-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; lipid binding

Biological Process: cholesterol metabolic process; lipid transport
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 Research Articles on HDLBP    1. progressively upregulated vigilin may serve as a molecular risk marker for hepatocellular carcinoma development, and targeting vigilin may help to inhibit hepatocellular carcinoma cell growth, survival and migration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-HDLBP antibodyOrgans/Tissues associated with anti-HDLBP antibody
 Disease Name  Pubmed Publications
 Microcephaly Antibodies  >1 publications with HDLBP and Microcephaly
 Breast Neoplasms Antibodies  >1 publications with HDLBP and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with HDLBP and Liver Diseases
 Immune System Diseases Antibodies  >1 publications with HDLBP and Immune System Diseases
 Nervous System Malformations Antibodies  >1 publications with HDLBP and Nervous System Malformations
 Fatty Liver Antibodies  >1 publications with HDLBP and Fatty Liver
 Congenital Abnormalities Antibodies  >1 publications with HDLBP and Congenital Abnormalities
 Nervous System Diseases Antibodies  >1 publications with HDLBP and Nervous System Diseases
 Autistic Disorder Antibodies  >1 publications with HDLBP and Autistic Disorder
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with HDLBP and Liver
 Bone Antibodies  >1 publications with HDLBP and Bone
 Ovary Antibodies  >1 publications with HDLBP and Ovary
 Prostate Antibodies  >1 publications with HDLBP and Prostate
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