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anti-HFE antibody :: Mouse HFE Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8527525 anti-HFE antibody
Unit / Price
0.1 mL  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HFE, Monoclonal Antibody

 Also Known As   

Mouse Monoclonal Antibody to HFE

 Product Synonym Names    HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; dJ221C16.10.1
 Product Gene Name   

anti-HFE antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176200
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    3F1D10
 Host    Mouse
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 Other Notes    Small volumes of anti-HFE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-HFE antibody   

Western Blot (WB), Immunocytochemistry (ICC)

 Application Notes for anti-HFE antibody    Western blot using Recombinant protein
Western blot using Transfection expressed protein
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NCBI/Uniprot data below describe general gene information for HFE. It may not necessarily be applicable to this product.
 NCBI GI #    695094697
 NCBI GeneID    3077
 NCBI Accession #    AIS82633.1 [Other Products]
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 UniProt Secondary Accession #    O75929; O75930; O75931; Q17RT0; Q96KU5; Q96KU6; Q96KU7; Q96KU8; Q9HC64; Q9HC68; B2CKL0 [Other Products]
 UniProt Related Accession #    Q30201 [Other Products]
 Molecular Weight    40kDa
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 NCBI Official Full Name    HFE, partial
 NCBI Official Synonym Full Names    homeostatic iron regulator
 NCBI Official Symbol    HFE [Similar Products]
 NCBI Official Synonym Symbols   
HH; HFE1; HLA-H; MVCD7; TFQTL2
[Similar Products]
 NCBI Protein Information    hereditary hemochromatosis protein
 UniProt Protein Name    Hereditary hemochromatosis protein
 UniProt Synonym Protein Names   
HLA-H
 Protein Family    Hereditary hemochromatosis protein
 UniProt Gene Name    HFE [Similar Products]
 UniProt Synonym Gene Names    HLAH [Similar Products]
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 NCBI Summary for HFE    The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HFE    Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
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 Research Articles on HFE    1. homozygosity for the HLA-A*03 allele significantly increases the risk of excessive iron loading in Norwegian p.C282Y homozygous male patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HFE antibodyPathways associated with anti-HFE antibody
 Reference Product  PubMed Publications
 HAMP antibody  >359 publications with HFE and HAMP
 TFR2 antibody  >239 publications with HFE and TFR2
 HFE2 antibody  >81 publications with HFE and HFE2
 SLC40A1 antibody  >74 publications with HFE and SLC40A1
 TFRC antibody  >24 publications with HFE and TFRC
 HLA-B antibody  >22 publications with HFE and HLA-B
 HLA-E antibody  >9 publications with HFE and HLA-E
 SLC11A2 antibody  >5 publications with HFE and SLC11A2
 B2M antibody  >3 publications with HFE and B2M
 Products by Pathway  Pathway Diagram
 Hfe Effect On Hepcidin Production Pathway antibodies  Hfe Effect On Hepcidin Production Pathway Diagram
Diseases associated with anti-HFE antibodyOrgans/Tissues associated with anti-HFE antibody
 Disease Name  Pubmed Publications
 Hemochromatosis Antibodies  >2782 publications with HFE and Hemochromatosis
 Liver Diseases Antibodies  >626 publications with HFE and Liver Diseases
 Anemia Antibodies  >271 publications with HFE and Anemia
 Fibrosis Antibodies  >196 publications with HFE and Fibrosis
 Hepatitis C Antibodies  >177 publications with HFE and Hepatitis C
 Nervous System Diseases Antibodies  >176 publications with HFE and Nervous System Diseases
 Inflammation Antibodies  >127 publications with HFE and Inflammation
 Carcinoma, Hepatocellular Antibodies  >124 publications with HFE and Carcinoma, Hepatocellular
 Heart Diseases Antibodies  >116 publications with HFE and Heart Diseases
 Fatty Liver Antibodies  >110 publications with HFE and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1253 publications with HFE and Blood
 Liver Antibodies  >1101 publications with HFE and Liver
 Intestine Antibodies  >115 publications with HFE and Intestine
 Brain Antibodies  >109 publications with HFE and Brain
 Skin Antibodies  >61 publications with HFE and Skin
 Spleen Antibodies  >52 publications with HFE and Spleen
 Kidney Antibodies  >47 publications with HFE and Kidney
 Lung Antibodies  >33 publications with HFE and Lung
 Eye Antibodies  >20 publications with HFE and Eye
 Stomach Antibodies  >20 publications with HFE and Stomach
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