View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse HIV-1 p66, Strain IIIB Monoclonal Antibody Catalog # MBS601420 Unit / Price 0.1 mg / $695 +1 FREE 8GB USB 5x0.1 mg / $2,960 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name HIV-1 p66, Strain IIIB, Monoclonal Antibody Popular Item Full Product Name HIV-1 p66, Strain IIIB (Reverse Transcriptase, Human Immunodeficiency Virus-1) Product Synonym Names Anti -HIV-1 p66, Strain IIIB (Reverse Transcriptase, Human Immunodeficiency Virus-1) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG Clone Number 5i7 (RT) Host Mouse Specificity Recognizes native and recombinant HIV-1 p66, Strain IIIB. Purity/Purification Purified, > 95% Form/Format Supplied as a liquid in PBS, pH 7.2. No stabilizers or preservatives added. Concentration 1mg/mL (lot specific) Immunogen Recombinant HIV-1 p66 Grade Highly Purified Preparation and Storage May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Other Notes Small volumes of anti-HIV-1 p66, Strain IIIB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-HIV-1 p66, Strain IIIB antibody Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: primarily, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genome is converted to double-stranded DNA by a virally encoded reverse transcriptase that is present in the virus particle. Product Categories/Family for anti-HIV-1 p66, Strain IIIB antibody Antibodies; Abs to Infectious Disease HIV Applications Tested/Suitable for anti-HIV-1 p66, Strain IIIB antibody ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization Application Notes for anti-HIV-1 p66, Strain IIIB antibody ELISA: 10-100ng/ml Western Blot: 1-5ug/mlNeutralization: Neutralizes HIV-1 p66, Strain IIIB as determined by HIV-1 p66 assay in vitro.Optimal dilutions to be determined by the researcher.Other applications not tested. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP