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anti-HIVEP2 antibody :: Mouse anti-Human HIVEP2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120441
Quality Control
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HIVEP2, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human HIVEP2

 Product Synonym Names    Homo sapiens human immunodeficiency virus type I enhancer binding protein 2 (HIVEP2), mRNA.; MBP-2; MIBP1; HIV-EP2
 Product Gene Name   

anti-HIVEP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    143054
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2418C2a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-HIVEP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-HIVEP2 antibody

   Members of the ZAS family, such as ZAS2 (HIVEP2), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb (Allen and Wu, 2004).[supplied by OMIM][NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-HIVEP2 antibody   

Dot Blot (DB)

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 Quality Control of anti-HIVEP2 antibody    Left: Western blot analysis of immunized recombinant protein, using anti-HIVEP2 monoclonal antibody.
anti-HIVEP2 antibody Quality Control image
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NCBI/Uniprot data below describe general gene information for HIVEP2. It may not necessarily be applicable to this product.
 NCBI GI #    110347462
 NCBI GeneID    3097
 NCBI Accession #    NP_006725.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_006734 [Other Products]
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 UniProt Secondary Accession #    Q02646; Q5THT5; Q9NS05 [Other Products]
 UniProt Related Accession #    P31629 [Other Products]
 Molecular Weight    269,053 Da
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 NCBI Official Full Name    Homo sapiens human immunodeficiency virus type I enhancer binding protein 2 (HIVEP2), mRNA
 NCBI Official Synonym Full Names    human immunodeficiency virus type I enhancer binding protein 2
 NCBI Official Symbol    HIVEP2 [Similar Products]
 NCBI Official Synonym Symbols   
SHN2; ZAS2; MBP-2; MIBP1; ZNF40B; HIV-EP2
[Similar Products]
 NCBI Protein Information    transcription factor HIVEP2; MHC binding protein-2; MHC-binding protein 2; Schnurri-2; c-myc intron binding protein 1; human immunodeficiency virus type I enhancer-binding protein 2
 UniProt Protein Name    Transcription factor HIVEP2
 UniProt Synonym Protein Names   
Human immunodeficiency virus type I enhancer-binding protein 2; HIV-EP2; MHC-binding protein 2; MBP-2
 Protein Family    Human immunodeficiency virus type I enhancer-binding protein
 UniProt Gene Name    HIVEP2 [Similar Products]
 UniProt Entry Name    ZEP2_HUMAN
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 NCBI Summary for HIVEP2    This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]
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 UniProt Comments for HIVEP2    HIVEP2: This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon- beta genes. It may act in T-cell activation.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 6q23-q24

Cellular Component: nucleoplasm

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
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 Research Articles on HIVEP2    1. a 154-amino acid region of MIBP1 was necessary for its O-GlcNAc transferase binding and O-GlcNAcylation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HIVEP2 antibodyDiseases associated with anti-HIVEP2 antibody
 Reference Product  PubMed Publications
 RFX1 antibody  >4 publications with HIVEP2 and RFX1
 CLIC4 antibody  >1 publications with HIVEP2 and CLIC4
 TCF4 antibody  >1 publications with HIVEP2 and TCF4
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with HIVEP2 and Inflammation
 Chromosome Aberrations Antibodies  >3 publications with HIVEP2 and Chromosome Aberrations
 Adenocarcinoma Antibodies  >2 publications with HIVEP2 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >2 publications with HIVEP2 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >2 publications with HIVEP2 and Breast Neoplasms
 Liver Neoplasms Antibodies  >2 publications with HIVEP2 and Liver Neoplasms
 Hepatitis Antibodies  >2 publications with HIVEP2 and Hepatitis
 Carcinoma, Squamous Cell Antibodies  >1 publications with HIVEP2 and Carcinoma, Squamous Cell
 Edema Antibodies  >1 publications with HIVEP2 and Edema
 Liver Diseases Antibodies  >1 publications with HIVEP2 and Liver Diseases
Organs/Tissues associated with anti-HIVEP2 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >15 publications with HIVEP2 and Bone
 Brain Antibodies  >12 publications with HIVEP2 and Brain
 Bone Marrow Antibodies  >7 publications with HIVEP2 and Bone Marrow
 Embryonic Tissue Antibodies  >4 publications with HIVEP2 and Embryonic Tissue
 Thymus Antibodies  >3 publications with HIVEP2 and Thymus
 Lung Antibodies  >3 publications with HIVEP2 and Lung
 Nerve Antibodies  >3 publications with HIVEP2 and Nerve
 Spleen Antibodies  >2 publications with HIVEP2 and Spleen
 Vascular Antibodies  >2 publications with HIVEP2 and Vascular
 Liver Antibodies  >2 publications with HIVEP2 and Liver
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