Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow HNRPLL rightarrow Monoclonal HNRPLL  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • HCCA2 Antibody
 • Malaria Pv mAb2-coating Antibody
 • Zika NS1 Recombinant Protein
 • Outer capsid protein VP4, partial Recombinant Protein
 • Glutathione S-Transferase (GST) Recombinant Protein
 • ALPL Antibody
 • Cytokeratin-18 (CK18) Antibody
 • immunoglobulin kappa variable 1-5 (IGKV1-5) ELISA Kit
 • Serum amyloid A (SAA1) Recombinant Protein
 • cytokine-like 1 (CYTL1) Antibody
 • VISA - MAVS Antibody
 • Signal peptide, CUB and EGF-like domain-containing protein 2... Recombinant Protein
 • Cyclosporine A (CsA) ELISA Kit
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-HNRPLL antibody :: Mouse anti-Human HNRPLL Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120513
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HNRPLL, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human HNRPLL

 Product Synonym Names    Homo sapiens heterogeneous nuclear ribonucleoprotein L-like(HNRPLL), mRNA.; SRRF
 Product Gene Name   

anti-HNRPLL antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    611208
Section Bar
 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    2432C3a
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Concentration    100 ug/ml (1.0 ml) (lot specific)
Section Bar
 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
Section Bar
 Other Notes    Small volumes of anti-HNRPLL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for anti-HNRPLL antibody

   HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM][NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-HNRPLL antibody   

Dot Blot (DB)

Section Bar
 Quality Control of anti-HNRPLL antibody    Western blot analysis of immunized recombinant protein, using anti-HNRPLL monoclonal antibody.
anti-HNRPLL antibody Quality Control image
Section Bar
 Quality Control #2 of anti-HNRPLL antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-HNRPLL antibody Quality Control #2 image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for HNRPLL. It may not necessarily be applicable to this product.
 NCBI GI #    217416377
 NCBI GeneID    92906
 NCBI Accession #    NP_612403.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_138394 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q96HR5 [Other Products]
 UniProt Related Accession #    Q8WVV9 [Other Products]
 Molecular Weight    56,467 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    heterogeneous nuclear ribonucleoprotein L-like
 NCBI Official Symbol    HNRNPLL [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    heterogeneous nuclear ribonucleoprotein L-like; stromal RNA regulating factor; stromal RNA-regulating factor
 UniProt Protein Name    Heterogeneous nuclear ribonucleoprotein L-like
 UniProt Synonym Protein Names   
Stromal RNA-regulating factor
 UniProt Gene Name    HNRNPLL [Similar Products]
 UniProt Entry Name    HNRLL_HUMAN
Section Bar
 NCBI Summary for HNRPLL    HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]
Section Bar
 UniProt Comments for HNRPLL    HNRPLL: RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. Interacts with HNRNPL. Up-regulated in stimulated T-cells. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 2p22.1

Cellular Component: membrane; nucleus; ribonucleoprotein complex

Molecular Function: mRNA binding; protein binding; nucleotide binding

Biological Process: mRNA processing; positive regulation of RNA splicing
Table BarTOPTable Bar
 Research Articles on HNRPLL    1. Loss-of-function mutation of hnRNPLL disrupts peripheral T cell accumulation even in the absence of CD45 protein, indicating that hnRNPLL acts through an independent mechanism to promote peripheral T cell longevity.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-HNRPLL antibodyDiseases associated with anti-HNRPLL antibody
 Reference Product  PubMed Publications
 PTPRC antibody  >6 publications with HNRPLL and PTPRC
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1 publications with HNRPLL and Immune System Diseases
 Lymphopenia Antibodies  >1 publications with HNRPLL and Lymphopenia
Organs/Tissues associated with anti-HNRPLL antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with HNRPLL and Blood
 Thymus Antibodies  >1 publications with HNRPLL and Thymus
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions