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anti-HOXC11 antibody :: Mouse anti-Human HOXC11 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120026
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HOXC11, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human HOXC11

 Product Synonym Names    Homo sapiens homeo box C11; MGC4906
 Product Gene Name   

anti-HOXC11 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605559
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    HOX5J232
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-HOXC11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HOXC11 antibody

   This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-HOXC11 antibody   

Dot Blot (DB)

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 Quality Control of anti-HOXC11 antibody    Western blot analysis of immunized recombinant protein, using anti-HOXC11 monoclonal antibody.
anti-HOXC11 antibody Quality Control image
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 Quality Control #2 of anti-HOXC11 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-HOXC11 antibody Quality Control #2 image
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NCBI/Uniprot data below describe general gene information for HOXC11. It may not necessarily be applicable to this product.
 NCBI GI #    16306725
 NCBI GeneID    3227
 NCBI Accession #    BC001543 [Other Products]
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 UniProt Secondary Accession #    Q96DH2; A8K7D1 [Other Products]
 UniProt Related Accession #    O43248 [Other Products]
 Molecular Weight    33,748 Da
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 NCBI Official Full Name    Homo sapiens homeobox C11, mRNA
 NCBI Official Synonym Full Names    homeobox C11
 NCBI Official Symbol    HOXC11 [Similar Products]
 NCBI Official Synonym Symbols   
HOX3H
[Similar Products]
 NCBI Protein Information    homeobox protein Hox-C11; homeo box C11; homeobox protein Hox-3H
 UniProt Protein Name    Homeobox protein Hox-C11
 UniProt Synonym Protein Names   
Homeobox protein Hox-3H
 Protein Family    Homeobox protein
 UniProt Gene Name    HOXC11 [Similar Products]
 UniProt Entry Name    HXC11_HUMAN
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 NCBI Summary for HOXC11    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HOXC11    HOXC11: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleoplasm; cytoplasm

Biological Process: anterior/posterior pattern formation; transcription, DNA-dependent; induction of an organ; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; metanephros development; proximal/distal pattern formation; endoderm development
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 Research Articles on HOXC11    1. HOXC11 and SRC-1 cooperate to regulate expression of the calcium-binding protein S100beta in resistant breast cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HOXC11 antibodyDiseases associated with anti-HOXC11 antibody
 Reference Product  PubMed Publications
 TBX4 antibody  >2 publications with HOXC11 and TBX4
 TBX2 antibody  >1 publications with HOXC11 and TBX2
 TBX5 antibody  >1 publications with HOXC11 and TBX5
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with HOXC11 and Breast Neoplasms
 Hematologic Diseases Antibodies  >1 publications with HOXC11 and Hematologic Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with HOXC11 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >1 publications with HOXC11 and Inflammation
Organs/Tissues associated with anti-HOXC11 antibody
 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >1 publications with HOXC11 and Uterus
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