BC001543
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,748 Da
NCBI Official Full Name
Homo sapiens homeobox C11, mRNA
NCBI Official Synonym Full Names
homeobox C11
NCBI Official Synonym Symbols
NCBI Protein Information
homeobox protein Hox-C11; homeo box C11; homeobox protein Hox-3H
UniProt Protein Name
Homeobox protein Hox-C11
UniProt Synonym Protein Names
Homeobox protein Hox-3H
UniProt Entry Name
HXC11_HUMAN
NCBI Summary for HOXC11
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for HOXC11
HOXC11: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. Belongs to the Abd-B homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: nucleoplasm; cytoplasm
Biological Process: anterior/posterior pattern formation; transcription, DNA-dependent; induction of an organ; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; metanephros development; proximal/distal pattern formation; endoderm development
Research Articles on HOXC11
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Products associated with anti-HOXC11 antibody
Diseases associated with anti-HOXC11 antibody
Organs/Tissues associated with anti-HOXC11 antibody
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