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anti-eltB antibody :: Mouse Heat Labile Enterotoxin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS834783 anti-eltB antibody
Unit / Price
0.5 mg  /  $375 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Heat Labile Enterotoxin (eltB), Monoclonal Antibody

 Also Known As   

Heat Labile Enterotoxin antibody

 Product Synonym Names    Monoclonal Heat Labile Enterotoxin; Anti-Heat Labile Enterotoxin; Enterotoxin
 Product Gene Name   

anti-eltB antibody

[Similar Products]
 Matching Pairs    Capture Antibody: Heat Labile Enterotoxin Clone #M120534 (MBS832798)
Detection Antibody: Heat Labile Enterotoxin Clone #M120535 (MBS834783)
Comments: Excellent pair for ELISA
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    M120535
 Host    Mouse
 Species Reactivity    No cross reactivity to Cholera toxin (CT)
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 Specificity    Reactive to Heat-labile enterotoxin (LT)
 Purity/Purification    > 95% pure
Heat Labile Enterotoxin antibody was purified by Protein A or G affinity purification
 Form/Format    Supplied as a liquid in PBS, pH 7.4, 3mM KCl, 1.5mM KH2PO4, 140mM NaCl, 8.0mM Na2HPO4
 Concentration    1-3 mg/ml (lot specific)
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 Biological Significance    Heat-labile enterotoxin is a type of labile toxin found in Escherichia coli that is inactivated at high temperatures. It acts similarly to the cholera toxin by raising cAMP levels through ADP-ribosylation of the alpha-subunit of a Gs protein leading to the constitutive activation of adenylate cyclase. Elevated cAMP levels stimulate secretion of Chloride ions and water from the enterocyte into the gut lumen, thus causing watery diarrhea. In addition to its effects on chloride secretion, which involve the same steps as the effects of cholera toxin, heat-labile enterotoxin binds additional substrates: lipopolysaccharide on the surface of E Coli cells and A-type blood antigens. The importance of these binding events is not yet known.
 Biohazard Information    This product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
 Immunogen    Heat Labile Enterotoxin antibody was raised in mouse using Heat-labile enterotoxin as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term or -20 degree C for longer storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-eltB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-eltB antibody

   Mouse monoclonal Heat Labile Enterotoxin antibody
 Product Categories/Family for anti-eltB antibody    Infectious Disease
 Applications Tested/Suitable for anti-eltB antibody   

ELISA (EIA)

 Application Notes for anti-eltB antibody    Use MBS834783 as the detection antibody with MBS832798 as the capture antibody in ELISA
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NCBI/Uniprot data below describe general gene information for eltB. It may not necessarily be applicable to this product.
 NCBI GI #    146376
 NCBI Accession #    AAA23973.1 [Other Products]
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 UniProt Secondary Accession #    P01557; P13768 [Other Products]
 Molecular Weight    14,133 Da [Similar Products]
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 NCBI Official Full Name    heat labile enterotoxin, partial
 UniProt Protein Name    Heat-labile enterotoxin B chain
 UniProt Synonym Protein Names   
LT-B, porcine; LTP-B
 UniProt Gene Name    eltB [Similar Products]
 UniProt Synonym Gene Names    ltpB [Similar Products]
 UniProt Entry Name    ELBP_ECOLX
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 UniProt Comments for eltB    The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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