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anti-HBE1 antibody :: Mouse Hemoglobin epsilon Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS834064 anti-HBE1 antibody
Unit / Price
0.1 mg  /  $625 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hemoglobin epsilon (HBE1), Monoclonal Antibody

 Also Known As   

Hemoglobin epsilon antibody (HRP)

 Product Synonym Names    Monoclonal Hemoglobin epsilon; Anti-Hemoglobin epsilon; HBE1; Hemoglobin
 Product Gene Name   

anti-HBE1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    142100
 3D Structure    ModBase 3D Structure for P02100
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 Clonality    Monoclonal
 Isotype    IgG1 kappa
 Clone Number    90050
 Host    Mouse
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 Specificity    Human
 Form/Format    Supplied in PBS, pH 7.4, with 0.05% NaN3
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 Biological Significance    The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5' - epsilon ? gamma-G ? gamma-A ? delta ? beta - 3'.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
 Tag/Conjugate    HRP
 Immunogen    Hemoglobin epsilon antibody was raised in mouse using hemoglobin Gower-I (a2e2) isolated from culture fluids of the cell line K562 as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-HBE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HBE1 antibody

   Mouse monoclonal Hemoglobin epsilon antibody (FITC)
 Product Categories/Family for anti-HBE1 antibody    Nutrition & Metabolism; Conjugated Monoclonal Antibodies
NCBI/Uniprot data below describe general gene information for HBE1. It may not necessarily be applicable to this product.
 NCBI GI #    4885393
 NCBI GeneID    3046
 NCBI Accession #    NP_005321.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005330.3 [Other Products]
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 UniProt Primary Accession #    P02100 [Other Products]
 UniProt Secondary Accession #    Q6FH44 [Other Products]
 UniProt Related Accession #    P02100 [Other Products]
 Molecular Weight    16,203 Da [Similar Products]
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 NCBI Official Full Name    hemoglobin subunit epsilon
 NCBI Official Synonym Full Names    hemoglobin, epsilon 1
 NCBI Official Symbol    HBE1 [Similar Products]
 NCBI Official Synonym Symbols   
HBE
[Similar Products]
 NCBI Protein Information    hemoglobin subunit epsilon
 UniProt Protein Name    Hemoglobin subunit epsilon
 UniProt Synonym Protein Names   
Epsilon-globin; Hemoglobin epsilon chain
 Protein Family    Hemoglobin
 UniProt Gene Name    HBE1 [Similar Products]
 UniProt Synonym Gene Names    HBE [Similar Products]
 UniProt Entry Name    HBE_HUMAN
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 NCBI Summary for HBE1    The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008]
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 UniProt Comments for HBE1    HBE1: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; hemoglobin alpha binding; oxygen binding; oxygen transporter activity

Biological Process: protein heterooligomerization; oxygen transport; negative regulation of transcription from RNA polymerase II promoter; blood coagulation
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 Research Articles on HBE1    1. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HBE1 antibodyPathways associated with anti-HBE1 antibody
 Reference Product  PubMed Publications
 HBB antibody  >4 publications with HBE1 and HBB
 HBD antibody  >3 publications with HBE1 and HBD
 HBG2 antibody  >2 publications with HBE1 and HBG2
 MAFG antibody  >1 publications with HBE1 and MAFG
 HBZ antibody  >1 publications with HBE1 and HBZ
 HBA2 antibody  >1 publications with HBE1 and HBA2
 HBA1 antibody  >1 publications with HBE1 and HBA1
 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-HBE1 antibodyOrgans/Tissues associated with anti-HBE1 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >5 publications with HBE1 and Carcinoma
 Inflammation Antibodies  >4 publications with HBE1 and Inflammation
 Liver Diseases Antibodies  >2 publications with HBE1 and Liver Diseases
 Necrosis Antibodies  >2 publications with HBE1 and Necrosis
 Intestinal Neoplasms Antibodies  >1 publications with HBE1 and Intestinal Neoplasms
 Brain Diseases Antibodies  >1 publications with HBE1 and Brain Diseases
 Abnormalities, Drug-Induced Antibodies  >1 publications with HBE1 and Abnormalities, Drug-Induced
 Leukemia, Myeloid Antibodies  >1 publications with HBE1 and Leukemia, Myeloid
 Hyperplasia Antibodies  >1 publications with HBE1 and Hyperplasia
 Carcinoma, Squamous Cell Antibodies  >1 publications with HBE1 and Carcinoma, Squamous Cell
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >32 publications with HBE1 and Lung
 Blood Antibodies  >3 publications with HBE1 and Blood
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