NP_000550.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,140 Da
NCBI Official Full Name
hemoglobin subunit gamma-1
NCBI Official Synonym Full Names
hemoglobin subunit gamma 1
NCBI Official Synonym Symbols
HBGA; HBGR; HBG-T2; HSGGL1; PRO2979 [Similar Products]
NCBI Protein Information
hemoglobin subunit gamma-1
UniProt Protein Name
Hemoglobin subunit gamma-1
UniProt Synonym Protein Names
Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain
NCBI Summary for HBG1
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
UniProt Comments for HBG1
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.CautionThe modification form of Leu-142 is subject of controversy and could be the artifactual result of sample handling.
Research Articles on HBG1
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Products associated with anti-HBG1 antibody
Pathways associated with anti-HBG1 antibody
Diseases associated with anti-HBG1 antibody
Organs/Tissues associated with anti-HBG1 antibody
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