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Mouse Hsp60 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS190473 anti-Hsp60 antibody
Unit / Price
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hsp60, Monoclonal Antibody

★Popular Item★
 Also Known As   

Anti-Hsp60 Monoclonal Antibody

 Product Synonym Names    Anti-Hsp60; Hsp60
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG1
 Host    Mouse
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 Specificity    Anti-Hsp60 [Mouse monoclonal antibody to human Hsp60]
This antibody recognizes human, mouse, rat, rabbit, bovine, canine, porcine, ovine, guinea pig, hamster, chicken, monkey, Xenopus, and Drosophila Hsp60 (60 kDa). It does not cross-react with bacterial or yeast Hsp60. The epitope recognized is within aa 383-447 of human Hsp60.
 Form/Format    100ug in PBS, pH 7.4, purified by Protein G affinity chromatography.
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 Antigen    Recombinant human Hsp60 expressed in E. coli.
 Preservatives    0.09% sodium azide
 Other Additives    50% glycerol
 Dilutions Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-Hsp60 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Hsp60 antibody

   Hsp60 is an abundant protein synthesized constitutively in various cell types that is induced to higher concentrations after cell shock. It is present in mitochondria of many mammalian species and has highly similar counterparts in bacteria and plants (where it is localized to chloroplasts). In general, Hsp60 proteins are present in high concentrations, are induced in response to environmental stresses (such as heat shock) are homo-oligomeric structures of 7 or 14 subunits that dissociate reversibly in the presence of Mg2+ and ATP, have ATPase activity, and play a role in folding and assembly of oligomeric protein structures. Hsp60 has been linked to Alzheimer's disease, coronary artery disease, multiple sclerosis, diabetes, and other autoimmune diseases.
 Product Categories/Family for anti-Hsp60 antibody    Heat Shock and Stress Proteins
 Applications Tested/Suitable for anti-Hsp60 antibody   

Flow Cytometry, Immunoblot, Immunoprecipitation

 Application Notes for anti-Hsp60 antibody    Immunoblotting: use at 0.1-1ug/ml. A band of ~60 kDa is detected.
Immunoprecipitation: use at 12.5ug/ml
Flow cytometry: use at 10ug/ml These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Heat-shocked HeLa cell lysate.
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NCBI/Uniprot data below describe general gene information for Hsp60. It may not necessarily be applicable to this product.
 NCBI GI #    441208
 NCBI Accession #    BAA03533.1 [Other Products]
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 NCBI Official Full Name    HSP60
 Protein Family    Hydrogenosomal chaperonin
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 UniProt Comments for Hsp60    Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Hsp60 antibodyPathways associated with anti-Hsp60 antibody
 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with Hsp60 and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with anti-Hsp60 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Hsp60 and Bone
 Connective Tissue Antibodies  >4 publications with Hsp60 and Connective Tissue
 Heart Antibodies  >3 publications with Hsp60 and Heart
 Muscle Antibodies  >3 publications with Hsp60 and Muscle
 Brain Antibodies  >3 publications with Hsp60 and Brain
 Vascular Antibodies  >2 publications with Hsp60 and Vascular
 Embryonic Tissue Antibodies  >2 publications with Hsp60 and Embryonic Tissue
 Ear Antibodies  >1 publications with Hsp60 and Ear
 Kidney Antibodies  >1 publications with Hsp60 and Kidney
 Umbilical Cord Antibodies  >1 publications with Hsp60 and Umbilical Cord
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