View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse Hypoxia Inducible Factor 1b Monoclonal Antibody Catalog # MBS603549 Unit / Price 0.1 mL / $710 +1 FREE 8GB USB 5x0.1 mL / $3,015 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Hypoxia Inducible Factor 1b, Monoclonal Antibody Full Product Name Hypoxia Inducible Factor 1b (HIF-1b, ARNT, Aryl hydrocarbon Receptor Nuclear Translocator) Product Synonym Names Anti -Hypoxia Inducible Factor 1b (HIF-1b, ARNT, Aryl hydrocarbon Receptor Nuclear Translocator) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG1,k Clone Number 3C145 Host Mouse Species Reactivity Bovine, Ferret, Human, Mouse, Rat, Sheep Specificity Recognizes human Hypoxia-inducible factor 1 beta (HIF-1 beta, ARNT) Species crossreactivity: Human, bovine, sheep, mouse, rat and ferret Purity/Purification Affinity PurifiedPurified by Protein G affinity chromatography. Form/Format Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide. Immunogen Fusion protein of human HIF-1beta Positive Control MCF7 human nuclear extracts Preparation and Storage May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of anti-Hypoxia Inducible Factor 1b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-Hypoxia Inducible Factor 1b antibody Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-1, a nuclear protein activating gene transcription in response to reduced cellular 02 concentration, activates the transcription of VEGF, EPO, iNOS, heme oxygenase 1 and other intracellular responses critical to hypoxia. HIF-1 is a heterodimer composed of HIF-1a and HIF-1b subunits. HIF-1a most closely resembles the Drosophila protein Sim. HIF-1b is a series of aryl hydrocarbon receptor nuclear translocator (ARNT) gene products. Product Categories/Family for anti-Hypoxia Inducible Factor 1b antibody Antibodies; Abs to Transcription Factors Applications Tested/Suitable for anti-Hypoxia Inducible Factor 1b antibody Western Blot (WB) TOP NCBI/Uniprot data below describe general gene information for Hypoxia Inducible Factor 1b. It may not necessarily be applicable to this product. NCBI GI # 5052000 TOP NCBI Official Full Name hypoxia-inducible factor 1b TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-Hypoxia Inducible Factor 1b antibody Reference Product PubMed Publications FLNA antibody >12 publications with Hypoxia Inducible Factor 1b and FLNA Pathways associated with anti-Hypoxia Inducible Factor 1b antibody Products by Pathway Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram MAPK Signaling Pathway antibodies MAPK Signaling Pathway Diagram MAPK Signaling Pathway antibodies MAPK Signaling Pathway Diagram Salmonella Infection Pathway antibodies Salmonella Infection Pathway Diagram Salmonella Infection Pathway antibodies Salmonella Infection Pathway Diagram Organs/Tissues associated with anti-Hypoxia Inducible Factor 1b antibody Organ/Tissue Name Pubmed Publications Bone Antibodies >13 publications with Hypoxia Inducible Factor 1b and Bone Connective Tissue Antibodies >4 publications with Hypoxia Inducible Factor 1b and Connective Tissue Heart Antibodies >3 publications with Hypoxia Inducible Factor 1b and Heart Muscle Antibodies >3 publications with Hypoxia Inducible Factor 1b and Muscle Brain Antibodies >3 publications with Hypoxia Inducible Factor 1b and Brain Vascular Antibodies >2 publications with Hypoxia Inducible Factor 1b and Vascular Embryonic Tissue Antibodies >2 publications with Hypoxia Inducible Factor 1b and Embryonic Tissue Ear Antibodies >1 publications with Hypoxia Inducible Factor 1b and Ear Kidney Antibodies >1 publications with Hypoxia Inducible Factor 1b and Kidney Umbilical Cord Antibodies >1 publications with Hypoxia Inducible Factor 1b and Umbilical Cord TOP