Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow IDO rightarrow Monoclonal IDO  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CD26 Antibody
 • ABCB11 Antibody
 • SLC25A27 cDNA Clone
 • Eosinophil chemotactic factor (ECF) ELISA Kit
 • Glucosidase Alpha, Acid (GaA) Antibody
 • Varicella-Zoster Virus (VZV) (gpIII) (VZVgH) Antibody
 • Dengue Virus Recombinant Protein
 • Toll Like Receptor 5 (TLR-5) ELISA Kit
 • Influenza B, Matrix Protein M1 Antibody
 • Beta-hexosaminidase subunit beta (Hexb) ELISA Kit
 • pro-opiomelanocortin, POMC ELISA Kit
 • EXT1 ELISA Kit
 • Peptidyl-prolyl cis-trans isomerase B (PPIB) ELISA Kit
 • HEPATITIS B SURFACE ANTIGEN Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-IDO antibody :: Mouse anti-Human, Mouse IDO Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8535057 anti-IDO antibody
Unit / Price
0.1 mL  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IDO, Monoclonal Antibody

 Also Known As   

IDO

 Product Synonym Names    Indoleamine-pyrrole 2; 3-dioxygenase
 Product Gene Name   

anti-IDO antibody

[Similar Products]
 Product Synonym Gene Name    IDO1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    147435
 3D Structure    ModBase 3D Structure for P14902
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    1G1
 Host    Mouse
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    ProA affinity purified
Section Bar
 Immunogen    Recombinant full length IDO of mouse origin.
 Storage Buffer    1*TBS (pH7.4), 1% BSA, 40% Glycerol.
 Preservative    0.05% Sodium Azide.
Section Bar
 Preparation and Storage    Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-IDO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-IDO antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for IDO. It may not necessarily be applicable to this product.
 NCBI GI #    4504577
 NCBI GeneID    3620
 NCBI Accession #    NP_002155.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002164.5 [Other Products]
Section Bar
 UniProt Primary Accession #    P14902 [Other Products]
 UniProt Secondary Accession #    Q540B4; E5RGR8; F6M9T7 [Other Products]
 UniProt Related Accession #    P14902 [Other Products]
 Molecular Weight    45,326 Da
Table BarTOPTable Bar
 NCBI Official Full Name    indoleamine 2,3-dioxygenase 1
 NCBI Official Synonym Full Names    indoleamine 2,3-dioxygenase 1
 NCBI Official Symbol    IDO1 [Similar Products]
 NCBI Official Synonym Symbols   
IDO; INDO; IDO-1
[Similar Products]
 NCBI Protein Information    indoleamine 2,3-dioxygenase 1
 UniProt Protein Name    Indoleamine 2,3-dioxygenase 1
 UniProt Synonym Protein Names   
Indoleamine-pyrrole 2,3-dioxygenase
 Protein Family    L-isoleucine-4-hydroxylase
 UniProt Gene Name    IDO1 [Similar Products]
 UniProt Synonym Gene Names    IDO; INDO; IDO-1 [Similar Products]
Section Bar
 NCBI Summary for IDO    This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Section Bar
 UniProt Comments for IDO    Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PubMed:25691885). Acts as a suppressor of anti-tumor immunity (PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan (PubMed:25691885). Protects the fetus from maternal immune rejection (PubMed:25691885).
Table BarTOPTable Bar
 Research Articles on IDO    1. main biological and actionable difference between OSCC from NSND and SD lies in the immune microenvironment, suggesting a higher clinical benefit of PD-L1 and IDO1 inhibition in OSCC from NSND
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-IDO antibodyPathways associated with anti-IDO antibody
 Reference Product  PubMed Publications
 KYNU antibody  >3 publications with IDO and KYNU
 CYP1A1 antibody  >2 publications with IDO and CYP1A1
 TPH1 antibody  >2 publications with IDO and TPH1
 CYP1A2 antibody  >1 publications with IDO and CYP1A2
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies  Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram
 L-kynurenine Degradation Pathway antibodies  L-kynurenine Degradation Pathway Diagram
 L-tryptophan Degradation III (eukaryotic) Pathway antibodies  L-tryptophan Degradation III (eukaryotic) Pathway Diagram
 L-tryptophan Degradation XI (mammalian, Via Kynurenine) Pathway antibodies  L-tryptophan Degradation XI (mammalian, Via Kynurenine) Pathway Diagram
 L-tryptophan Degradation To 2-amino-3-carboxymuconate Semialdehyde Pathway antibodies  L-tryptophan Degradation To 2-amino-3-carboxymuconate Semialdehyde Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
Diseases associated with anti-IDO antibodyOrgans/Tissues associated with anti-IDO antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >68 publications with IDO and Inflammation
 Neoplasms, Experimental Antibodies  >12 publications with IDO and Neoplasms, Experimental
 Colitis Antibodies  >11 publications with IDO and Colitis
 Neurodegenerative Diseases Antibodies  >8 publications with IDO and Neurodegenerative Diseases
 Lung Diseases Antibodies  >8 publications with IDO and Lung Diseases
 Necrosis Antibodies  >7 publications with IDO and Necrosis
 Liver Diseases Antibodies  >6 publications with IDO and Liver Diseases
 Breast Neoplasms Antibodies  >6 publications with IDO and Breast Neoplasms
 Cognition Disorders Antibodies  >4 publications with IDO and Cognition Disorders
 Endometriosis Antibodies  >4 publications with IDO and Endometriosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with IDO and Brain
 Bone Antibodies  >20 publications with IDO and Bone
 Lung Antibodies  >18 publications with IDO and Lung
 Liver Antibodies  >12 publications with IDO and Liver
 Intestine Antibodies  >8 publications with IDO and Intestine
 Uterus Antibodies  >7 publications with IDO and Uterus
 Kidney Antibodies  >6 publications with IDO and Kidney
 Placenta Antibodies  >6 publications with IDO and Placenta
 Embryonic Tissue Antibodies  >4 publications with IDO and Embryonic Tissue
 Eye Antibodies  >4 publications with IDO and Eye
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions