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anti-IFN BETA antibody :: Mouse IFN BETA Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS214516 anti-IFN BETA antibody
Unit / Price
0.2 mg  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IFN BETA, Monoclonal Antibody

 Also Known As   

MOUSE ANTI HUMAN IFN BETA

 Product Gene Name   

anti-IFN BETA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147640
 3D Structure    ModBase 3D Structure for P01574
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    BG6
 Host    Mouse
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 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 1 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide
Preparation
 Immunogen    Recombinant full size human IFN Beta, expressed in E Coli.
Fusion Partners
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-IFN BETA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-IFN BETA antibody

   Mouse anti Human IFN beta antibody, clone BG6 recognizes human interferon beta (IFN Beta), a 22kDa cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis. Mouse anti Human IFN beta antibody, clone BG6 recognizes glycosylated and non-glycosylated human IFNB and there is no cross-reactivity with human interferon alpha or human interferon gamma.
 Applications Tested/Suitable for anti-IFN BETA antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for IFN BETA. It may not necessarily be applicable to this product.
 NCBI GI #    4504603
 NCBI GeneID    3456
 NCBI Accession #    NP_002167.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002176.2 [Other Products]
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 UniProt Primary Accession #    P01574 [Other Products]
 UniProt Secondary Accession #    Q5VWC9 [Other Products]
 UniProt Related Accession #    P01574 [Other Products]
 Molecular Weight    22,294 Da
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 NCBI Official Full Name    interferon beta
 NCBI Official Synonym Full Names    interferon, beta 1, fibroblast
 NCBI Official Symbol    IFNB1 [Similar Products]
 NCBI Official Synonym Symbols   
IFB; IFF; IFNB
[Similar Products]
 NCBI Protein Information    interferon beta; IFN-beta; fibroblast interferon
 UniProt Protein Name    Interferon beta
 UniProt Synonym Protein Names   
Fibroblast interferon
 UniProt Gene Name    IFNB1 [Similar Products]
 UniProt Synonym Gene Names    IFB; IFNB; IFN-beta [Similar Products]
 UniProt Entry Name    IFNB_HUMAN
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 UniProt Comments for IFN BETA    IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21

Cellular Component: extracellular space; extracellular region

Molecular Function: interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; response to virus; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; cell surface receptor linked signal transduction; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein; B cell activation during immune response
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 Research Articles on IFN BETA    1. A20 has a novel atheroprotective function in vascular cells through modulation of IFNgamma/STAT1 signaling in an IFNbeta-dependent, but NF-kappaB-independent, manner
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IFN BETA antibodyPathways associated with anti-IFN BETA antibody
 Reference Product  PubMed Publications
 IRF3 antibody  >18 publications with IFN BETA and IRF3
 IFNAR1 antibody  >6 publications with IFN BETA and IFNAR1
 IRF7 antibody  >4 publications with IFN BETA and IRF7
 STAT2 antibody  >3 publications with IFN BETA and STAT2
 EP300 antibody  >1 publications with IFN BETA and EP300
 CREBBP antibody  >1 publications with IFN BETA and CREBBP
 IRF1 antibody  >1 publications with IFN BETA and IRF1
 IFNAR2 antibody  >1 publications with IFN BETA and IFNAR2
 Products by Pathway  Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
Diseases associated with anti-IFN BETA antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >9 publications with IFN BETA and Immune System Diseases
 Inflammation Antibodies  >8 publications with IFN BETA and Inflammation
 Necrosis Antibodies  >7 publications with IFN BETA and Necrosis
 Carcinoma Antibodies  >4 publications with IFN BETA and Carcinoma
 Melanoma Antibodies  >3 publications with IFN BETA and Melanoma
 Leukemia Antibodies  >3 publications with IFN BETA and Leukemia
 Lung Neoplasms Antibodies  >3 publications with IFN BETA and Lung Neoplasms
 Heart Diseases Antibodies  >2 publications with IFN BETA and Heart Diseases
 Multiple Sclerosis Antibodies  >2 publications with IFN BETA and Multiple Sclerosis
 Pancreatic Neoplasms Antibodies  >2 publications with IFN BETA and Pancreatic Neoplasms
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