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anti-IFN beta antibody :: Mouse anti-Human IFN beta Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS530525 anti-IFN beta antibody
Unit / Price
0.05 mg  /  $315 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IFN beta, Monoclonal Antibody

 Also Known As   

IFN beta antibody

 Product Synonym Names    Monoclonal IFN beta; Anti-IFN beta; Leukocyte interferon; Interferon beta; Type I interferon; B cell interferon; RMMB1
 Product Gene Name   

anti-IFN beta antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147640
 3D Structure    ModBase 3D Structure for P01574
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 Clonality    Monoclonal
 Isotype    IgG2a kappa
 Clone Number    M99012525
 Host    Mouse
 Species Reactivity    Human
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 Form/Format    Purified monoclonal supplied in PBS, pH 7.4, with 0.1% BSA.
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 Biological Significance    Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.
 Bioactivity    Binds to human interferon beta with high affinity
 Immunogen    IFN beta antibody was raised in mouse using human interferon beta as the immunogen.
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 Preparation and Storage    Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
 Other Notes    Small volumes of anti-IFN beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IFN beta antibody

   Mouse monoclonal IFN beta antibody
 Product Categories/Family for anti-IFN beta antibody    Immunology
 Applications Tested/Suitable for anti-IFN beta antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for IFN beta. It may not necessarily be applicable to this product.
 NCBI GI #    4504603
 NCBI GeneID    3456
 NCBI Accession #    NP_002167.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002176.2 [Other Products]
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 UniProt Primary Accession #    P01574 [Other Products]
 UniProt Secondary Accession #    Q5VWC9 [Other Products]
 UniProt Related Accession #    P01574 [Other Products]
 Molecular Weight    22,294 Da
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 NCBI Official Full Name    interferon beta
 NCBI Official Synonym Full Names    interferon, beta 1, fibroblast
 NCBI Official Symbol    IFNB1 [Similar Products]
 NCBI Official Synonym Symbols   
IFB; IFF; IFNB
[Similar Products]
 NCBI Protein Information    interferon beta
 UniProt Protein Name    Interferon beta
 UniProt Synonym Protein Names   
Fibroblast interferon
 UniProt Gene Name    IFNB1 [Similar Products]
 UniProt Synonym Gene Names    IFB; IFNB; IFN-beta [Similar Products]
 UniProt Entry Name    IFNB_HUMAN
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 UniProt Comments for IFN beta    IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9p21

Cellular Component: extracellular space; extracellular region

Molecular Function: interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; response to virus; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; cell surface receptor linked signal transduction; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; B cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein
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 Research Articles on IFN beta    1. In an expression screen for proteins that can activate the IFNB1 promoter, authors identified the ER-associated protein ZDHHC1 as a positive regulator of virus-triggered, MITA/STING-dependent immune signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IFN beta antibodyPathways associated with anti-IFN beta antibody
 Reference Product  PubMed Publications
 IRF3 antibody  >18 publications with IFN beta and IRF3
 IFNAR1 antibody  >6 publications with IFN beta and IFNAR1
 STAT1 antibody  >5 publications with IFN beta and STAT1
 IRF7 antibody  >4 publications with IFN beta and IRF7
 STAT2 antibody  >3 publications with IFN beta and STAT2
 IRF1 antibody  >1 publications with IFN beta and IRF1
 IFNAR2 antibody  >1 publications with IFN beta and IFNAR2
 SOCS3 antibody  >1 publications with IFN beta and SOCS3
 Products by Pathway  Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
Diseases associated with anti-IFN beta antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >9 publications with IFN beta and Immune System Diseases
 Inflammation Antibodies  >8 publications with IFN beta and Inflammation
 Necrosis Antibodies  >7 publications with IFN beta and Necrosis
 Lung Diseases Antibodies  >7 publications with IFN beta and Lung Diseases
 Carcinoma Antibodies  >4 publications with IFN beta and Carcinoma
 Melanoma Antibodies  >3 publications with IFN beta and Melanoma
 Lung Neoplasms Antibodies  >3 publications with IFN beta and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with IFN beta and Neoplasms, Experimental
 Multiple Sclerosis Antibodies  >2 publications with IFN beta and Multiple Sclerosis
 Pancreatic Neoplasms Antibodies  >2 publications with IFN beta and Pancreatic Neoplasms
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