P18893.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,641 Da
NCBI Official Full Name
Interleukin-10
NCBI Official Synonym Full Names
interleukin 10
NCBI Official Synonym Symbols
NCBI Protein Information
interleukin-10; cytokine synthesis inhibitory factor
UniProt Protein Name
Interleukin-10
UniProt Synonym Protein Names
Cytokine synthesis inhibitory factor; CSIF
UniProt Synonym Gene Names
UniProt Entry Name
IL10_MOUSE
UniProt Comments for IL-10
IL10: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. Belongs to the IL-10 family.
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide; Cytokine
Cellular Component: extracellular space; extracellular region
Molecular Function: cytokine activity; interleukin-10 receptor binding
Biological Process: negative regulation of chronic inflammatory response to antigenic stimulus; positive regulation of transcription, DNA-dependent; response to glucocorticoid stimulus; positive regulation of JAK-STAT cascade; negative regulation of B cell proliferation; negative regulation of membrane protein ectodomain proteolysis; response to molecule of bacterial origin; positive regulation of MHC class II biosynthetic process; negative regulation of interferon-gamma production; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor biosynthetic process; inflammatory response; negative regulation of interleukin-12 production; positive regulation of B cell apoptosis; negative regulation of myeloid dendritic cell activation; negative regulation of nitric oxide biosynthetic process; negative regulation of tumor necrosis factor production; negative regulation of cytokine secretion during immune response; regulation of gene expression; negative regulation of inflammatory response; defense response to bacterium; negative regulation of cytokine production; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; immune response; regulation of sensory perception of pain; receptor biosynthetic process; positive regulation of cytokine secretion; negative regulation of apoptosis
Research Articles on IL-10
Precautions
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Disclaimer
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Pathways associated with anti-IL-10 antibody
Diseases associated with anti-IL-10 antibody
Organs/Tissues associated with anti-IL-10 antibody
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