NP_999288.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
interleukin-4
NCBI Protein Information
interleukin-4; IL-4; BSF-1; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1
UniProt Protein Name
Interleukin-4
UniProt Synonym Protein Names
B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1
UniProt Entry Name
IL4_PIG
UniProt Comments for IL4
Function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-4/IL-13 family.
Product References and Citations for anti-IL4 antibody
1. Chretien, I., A.V. Kimmenade, M.K. Pearce, J. Banchereau, and J.S. Abrams. 1989. J. Immunol. Meth. 117:67. 2. Ramanathan, L., R. Ingram, L. Sullivan, R. Greenberg, R. Reim, P. Trotta, and H. Lee. 1993. Biochem. 32:3549. 3. Abrams, J.S., M.-G. Roncarolo, H.. Yssel, U. Andersson, G.J. Gleich, and J.E., Silver. 1992. Immunol. Rev. 127:5.
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Pathways associated with anti-IL4 antibody
Diseases associated with anti-IL4 antibody
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