View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-IL11 antibody :: Mouse anti-Human IL-11 IL11 Monoclonal Antibody Catalog # MBS532164 Unit / Price 0.5 mg / $380 +1 FREE 8GB USB 5x0.5 mg / $1,535 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IL11, Monoclonal Antibody Popular Item Full Product Name IL11 antibody Product Synonym Names Monoclonal IL11; Anti-IL11; IL-11; Adipogenesis inhibitory factor; IL11; Interleukin 11; IL 11; AGIF Product Gene Name anti-IL11 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 147681 3D Structure ModBase 3D Structure for P20809 Clonality Monoclonal Isotype IgG1 kappa Clone Number M912271 Host Mouse Species Reactivity Human IL-11 Specificity Human IL-11 Form/Format Sterile filtered antibody solution was lyophilized from PBS. Concentration .5 mg/ml (lot specific) Immunogen E.coli derived Recombinant Human IL-11 Endotoxin <0.1 ng/ug of protein (<1EU/ug). Preparation and Storage Ships at ambient or refrigerated. Upon receipt, store at 4°C short term, -20°C long term. Avoid repeated freeze/thaw cycles. Other Notes Small volumes of anti-IL11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-IL11 antibody Mouse monoclonal IL11 antibody Product Categories/Family for anti-IL11 antibody Cytokines & Growth Factors Applications Tested/Suitable for anti-IL11 antibody Sandwich ELISA (EIA), Immunostaining, Neutralization TOP NCBI/Uniprot data below describe general gene information for IL11. It may not necessarily be applicable to this product. NCBI GI # 10834994 NCBI GeneID 3589 NCBI Accession # NP_000632.1 [Other Products] NCBI GenBank Nucleotide # NM_000641.3 [Other Products] UniProt Primary Accession # P20809 [Other Products] UniProt Secondary Accession # Q96EB4; B4DQV5[Other Products] UniProt Related Accession # P20809[Other Products] Molecular Weight Approximately 150kDa TOP NCBI Official Full Name interleukin-11 isoform 1 NCBI Official Synonym Full Names interleukin 11 NCBI Official Symbol IL11 [Similar Products] NCBI Official Synonym Symbols AGIF; IL-11 [Similar Products] NCBI Protein Information interleukin-11 UniProt Protein Name Interleukin-11 UniProt Synonym Protein Names Adipogenesis inhibitory factor Protein Family Interleukin UniProt Gene Name IL11 [Similar Products] UniProt Synonym Gene Names AGIF [Similar Products] UniProt Entry Name IL11_HUMAN TOP NCBI Summary for IL11 The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012] TOP UniProt Comments for IL11 IL11: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Belongs to the IL-6 superfamily.Protein type: Secreted, signal peptide; Cell cycle regulation; Motility/polarity/chemotaxis; CytokineChromosomal Location of Human Ortholog: 19q13.3-q13.4Cellular Component: extracellular space; cytoplasm; extracellular regionMolecular Function: growth factor activity; cytokine activity; interleukin-11 receptor bindingBiological Process: fat cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; positive regulation of MAPKKK cascade; megakaryocyte differentiation; negative regulation of hormone secretion; B cell differentiation; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation Research Articles on IL11 1. Low serum interleukin-11 are associated with pancreatic cancer. 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TOP Products associated with anti-IL11 antibody Reference Product PubMed Publications IL11RA antibody >98 publications with IL11 and IL11RA STAT3 antibody >96 publications with IL11 and STAT3 IL6ST antibody >85 publications with IL11 and IL6ST OSM antibody >81 publications with IL11 and OSM CNTF antibody >72 publications with IL11 and CNTF IL6 antibody >37 publications with IL11 and IL6 MPL antibody >26 publications with IL11 and MPL LIFR antibody >23 publications with IL11 and LIFR IL13RA1 antibody >1 publications with IL11 and IL13RA1 Pathways associated with anti-IL11 antibody Products by Pathway Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Hematopoietic Cell Lineage Pathway antibodies Hematopoietic Cell Lineage Pathway Diagram Hematopoietic Cell Lineage Pathway antibodies Hematopoietic Cell Lineage Pathway Diagram Integrated Pancreatic Cancer Pathway antibodies Integrated Pancreatic Cancer Pathway Diagram Interleukin-11 Signaling Pathway antibodies Interleukin-11 Signaling Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Jak-STAT Signaling Pathway antibodies Jak-STAT Signaling Pathway Diagram Rheumatoid Arthritis Pathway antibodies Rheumatoid Arthritis Pathway Diagram Rheumatoid Arthritis Pathway antibodies Rheumatoid Arthritis Pathway Diagram Diseases associated with anti-IL11 antibody Disease Name Pubmed Publications Inflammation Antibodies >170 publications with IL11 and Inflammation Necrosis Antibodies >155 publications with IL11 and Necrosis Lung Diseases Antibodies >63 publications with IL11 and Lung Diseases Breast Neoplasms Antibodies >59 publications with IL11 and Breast Neoplasms Cardiovascular Diseases Antibodies >53 publications with IL11 and Cardiovascular Diseases Liver Diseases Antibodies >40 publications with IL11 and Liver Diseases Anemia Antibodies >37 publications with IL11 and Anemia Hemorrhage Antibodies >35 publications with IL11 and Hemorrhage Fibrosis Antibodies >31 publications with IL11 and Fibrosis Edema Antibodies >30 publications with IL11 and Edema Organs/Tissues associated with anti-IL11 antibody Organ/Tissue Name Pubmed Publications Intestine Antibodies >68 publications with IL11 and Intestine Connective Tissue Antibodies >57 publications with IL11 and Connective Tissue Vascular Antibodies >55 publications with IL11 and Vascular Brain Antibodies >49 publications with IL11 and Brain Embryonic Tissue Antibodies >45 publications with IL11 and Embryonic Tissue Kidney Antibodies >36 publications with IL11 and Kidney Skin Antibodies >31 publications with IL11 and Skin Stomach Antibodies >27 publications with IL11 and Stomach Prostate Antibodies >16 publications with IL11 and Prostate Pancreas Antibodies >8 publications with IL11 and Pancreas TOP © 2006-24 MyBioSource.com. 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