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anti-IL25 antibody :: Mouse anti-Human, Mouse IL25 / IL17E Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS245013
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL25 / IL17E, Monoclonal Antibody

★Popular Item★
 Also Known As   

Mouse Monoclonal [clone 68C1039.2] (IgG1) to Human IL25 / IL17E

 Product Synonym Names    Anti-IL25 / IL17E Antibody (aa115-132, clone 68C1039.2) IHC-plus; IL25; Interleukin 17E; Interleukin 25; Interleukin-25; IL17E; IL-17E; IL-25; Interleukin-17E; Human IL25; IL17E
 Product Gene Name   

anti-IL25 antibody

[Similar Products]
 Product Synonym Gene Name    IL17E [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605658
 3D Structure    ModBase 3D Structure for Q9H293
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    68C1039.2
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Specificity    A synthetic peptide of amino acids 115-132, obtained from the human IL-17E protein sequence, was used as immunogen
 Purity/Purification    Protein G Purified
 Form/Format    PBS containing 0.05% BSA and 0.05% sodium azide. Sourced in TCS.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human IL25 / IL-25.
 Immunogen Type    Synthetic peptide
 Immunogen    IL25 / IL17E antibody was raised against synthetic peptide from human IL25 / IL-25.
 Antigen Modification    aa115-132
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 Preparation and Storage    Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
 Other Notes    Small volumes of anti-IL25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IL25 antibody

   The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8.
 Product Categories/Family for anti-IL25 antibody    Family: Interleukin
 Applications Tested/Suitable for anti-IL25 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-IL25 antibody    IHC-P (10 ug/ml), WB (2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-IL25 antibody    Anti-IL-25 antibody IHC of human adrenal cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-IL25 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IL25. It may not necessarily be applicable to this product.
 NCBI GI #    12232485
 NCBI GeneID    64806
 NCBI Accession #    NP_073626.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022789.3 [Other Products]
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 UniProt Primary Accession #    Q9H293 [Other Products]
 UniProt Secondary Accession #    Q2M3F0; Q8IZV3; Q8WXB0 [Other Products]
 UniProt Related Accession #    Q9H293 [Other Products]
 Molecular Weight    18,523 Da
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 NCBI Official Full Name    interleukin-25 isoform 1
 NCBI Official Synonym Full Names    interleukin 25
 NCBI Official Symbol    IL25 [Similar Products]
 NCBI Official Synonym Symbols   
IL17E
[Similar Products]
 NCBI Protein Information    interleukin-25; interleukin-17E
 UniProt Protein Name    Interleukin-25
 UniProt Synonym Protein Names   
Interleukin-17E; IL-17E
 Protein Family    Interleukin
 UniProt Gene Name    IL25 [Similar Products]
 UniProt Synonym Gene Names    IL17E; IL-25; IL-17E [Similar Products]
 UniProt Entry Name    IL25_HUMAN
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 NCBI Summary for IL25    The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
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 UniProt Comments for IL25    IL25: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Belongs to the IL-17 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular space

Molecular Function: cytokine activity; interleukin-17E receptor binding

Biological Process: response to fungus; inflammatory response to antigenic stimulus; response to nematode; eosinophil differentiation; positive regulation of transcription from RNA polymerase II promoter
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 Research Articles on IL25    1. Because IL-25 has a major role in triggering type 2 responses, bronchial epithelial IL-25 expression is likely a key determinant of type 2 response activation in asthma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL25 antibodyPathways associated with anti-IL25 antibody
 Reference Product  PubMed Publications
 IL33 antibody  >14 publications with IL25 and IL33
 IL17RB antibody  >3 publications with IL25 and IL17RB
 ITGAX antibody  >2 publications with IL25 and ITGAX
 IL23A antibody  >1 publications with IL25 and IL23A
 CCL11 antibody  >1 publications with IL25 and CCL11
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL17 Signaling Pathway antibodies  IL17 Signaling Pathway Diagram
Diseases associated with anti-IL25 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >33 publications with IL25 and Inflammation
 Hypersensitivity Antibodies  >28 publications with IL25 and Hypersensitivity
 Lung Diseases Antibodies  >19 publications with IL25 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >14 publications with IL25 and Respiratory Hypersensitivity
 Hyperplasia Antibodies  >7 publications with IL25 and Hyperplasia
 Dermatitis, Atopic Antibodies  >7 publications with IL25 and Dermatitis, Atopic
 Necrosis Antibodies  >4 publications with IL25 and Necrosis
 Colitis Antibodies  >4 publications with IL25 and Colitis
 Liver Diseases Antibodies  >2 publications with IL25 and Liver Diseases
 Death Antibodies  >2 publications with IL25 and Death
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