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anti-IL3 antibody :: Mouse anti-Human IL3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS531529 anti-IL3 antibody
Unit / Price
0.25 mg  /  $160 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL3, Monoclonal Antibody

 Also Known As   

IL3 antibody

 Product Synonym Names    Monoclonal IL3; Anti-IL3; IL 3; IL-3; Interleukin-3; IL3
 Product Gene Name   

anti-IL3 antibody

[Similar Products]
 Matching Pairs    Capture Antibody: IL3 Clone #M313121 (MBS531529)
Detection Antibody: IL3 Clone #M313122 (MBS531405)
Comments: For use in sandwich immunoassay
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147740
 3D Structure    ModBase 3D Structure for P08700
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    M313121
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    IL3 antibody was purified by chromatography on protein G Sepharose.
 Form/Format    Purified murine ascites supplied in PBS, pH 7.2, 0.1 % NaN3.
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 Biological Significance    Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells as well as stimulates proliferation of all cells in the myeloid lineage.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
 Immunogen    IL3 antibody was raised in mouse using recombinant human IL-3 as the immunogen.
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 Preparation and Storage    Store at 4 degree C.
 Other Notes    Small volumes of anti-IL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IL3 antibody

   Mouse monoclonal IL3 antibody
 Product Categories/Family for anti-IL3 antibody    Cytokines & Growth Factors
 Applications Tested/Suitable for anti-IL3 antibody   


 Application Notes for anti-IL3 antibody    MBS531529 can be used as the coating antibody along with MBS531405 as the detection antibody
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NCBI/Uniprot data below describe general gene information for IL3. It may not necessarily be applicable to this product.
 NCBI GI #    28416915
 NCBI GeneID    3562
 NCBI Accession #    NP_000579.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000588.3 [Other Products]
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 UniProt Primary Accession #    P08700 [Other Products]
 UniProt Secondary Accession #    Q6GS87 [Other Products]
 UniProt Related Accession #    P08700 [Other Products]
 Molecular Weight    17,233 Da
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 NCBI Official Full Name    interleukin-3
 NCBI Official Synonym Full Names    interleukin 3
 NCBI Official Symbol    IL3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    interleukin-3
 UniProt Protein Name    Interleukin-3
 UniProt Synonym Protein Names   
Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
 Protein Family    Interleukin
 UniProt Gene Name    IL3 [Similar Products]
 UniProt Synonym Gene Names    IL-3; MCGF [Similar Products]
 UniProt Entry Name    IL3_HUMAN
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 NCBI Summary for IL3    The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL3    IL3: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family.

Protein type: Secreted, signal peptide; Cell cycle regulation; Apoptosis; Oncoprotein; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-3 receptor binding; growth factor activity; cytokine activity

Biological Process: nervous system development; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; positive regulation of tyrosine phosphorylation of Stat5 protein; embryonic hemopoiesis; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; immune response; positive regulation of myeloid leukocyte differentiation; positive regulation of DNA replication
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 Research Articles on IL3    1. findings showed that high plasma IL-3 levels are associated with high mortality in sepsis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL3 antibodyPathways associated with anti-IL3 antibody
 Reference Product  PubMed Publications
 IL5 antibody  >50 publications with IL3 and IL5
 IL13 antibody  >19 publications with IL3 and IL13
 JAK2 antibody  >13 publications with IL3 and JAK2
 CSF2RB antibody  >10 publications with IL3 and CSF2RB
 IL3RA antibody  >8 publications with IL3 and IL3RA
 FOS antibody  >7 publications with IL3 and FOS
 STAT5A antibody  >4 publications with IL3 and STAT5A
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
Diseases associated with anti-IL3 antibodyOrgans/Tissues associated with anti-IL3 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >31 publications with IL3 and Necrosis
 Disease Models, Animal Antibodies  >31 publications with IL3 and Disease Models, Animal
 Lung Diseases Antibodies  >24 publications with IL3 and Lung Diseases
 Inflammation Antibodies  >21 publications with IL3 and Inflammation
 Neoplasms, Experimental Antibodies  >21 publications with IL3 and Neoplasms, Experimental
 Asthma Antibodies  >17 publications with IL3 and Asthma
 Anemia Antibodies  >12 publications with IL3 and Anemia
 Nervous System Diseases Antibodies  >10 publications with IL3 and Nervous System Diseases
 Kidney Diseases Antibodies  >6 publications with IL3 and Kidney Diseases
 Lung Neoplasms Antibodies  >5 publications with IL3 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >13 publications with IL3 and Mixed
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