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anti-NP antibody :: Mouse INFLUENZA A Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211419 anti-NP antibody
Unit / Price
0.2 mg  /  $455 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

INFLUENZA A (NP), Monoclonal Antibody

★Popular Item★
 Also Known As   

MOUSE ANTI INFLUENZA A

 Product Gene Name   

anti-NP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P18072
 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    1331
 Host    Mouse
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 Form/Format    Purified
Purified IgG - liquid
 Concentration    Approximate Protein Concentration: 1.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
 Preparation    Purified IgG prepared by affinity chromatography on Protein A
 Immunogen    Influenza virus from Texas strain.
 Buffer Solution    Phosphate buffered saline
 Target Species    Viral
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-NP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NP antibody

   Mouse anti Influenza A, clone 1331, recognizes the nucleoprotein of Influenza A. It has been found reactive with over 50 isolates from H1 through to H14 and gives 'nuclear' staining in immunofluorescence.
 Applications Tested/Suitable for anti-NP antibody   

Immunohistology Frozen, ELISA (EIA), Immunofluorescence (IF)

 Application Notes for anti-NP antibody    Immunohistology - Frozen: Minimum Dilution: 1/100; Maximum Dilution: 1/500;
ELISA: Minimum Dilution: 1/200; Maximum Dilution: 1/2000;
Immunofluorescence: Minimum Dilution: 1/100; Maximum Dilution: 1/500
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NCBI/Uniprot data below describe general gene information for NP. It may not necessarily be applicable to this product.
 NCBI GI #    139085
 NCBI Accession #    P18072.1 [Other Products]
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 UniProt Primary Accession #    P18072 [Other Products]
 Molecular Weight    56,212 Da [Similar Products]
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 NCBI Official Full Name    Nucleoprotein
 UniProt Protein Name    Nucleoprotein
 UniProt Synonym Protein Names   
Nucleocapsid protein; Protein N
 Protein Family    Nucleoprotein
 UniProt Gene Name    NP [Similar Products]
 UniProt Synonym Gene Names    Protein N [Similar Products]
 UniProt Entry Name    NCAP_I77AH
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 UniProt Comments for NP    Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus ().
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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