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anti-ITGB5 antibody :: Mouse anti-Chicken INTEGRIN ALPHA V BETA 5 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211733 anti-ITGB5 antibody
Unit / Price
0.1 mg  /  $1,055 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

INTEGRIN ALPHA V BETA 5 (ITGB5), Monoclonal Antibody

 Also Known As   

MOUSE ANTI HUMAN INTEGRIN ALPHA V BETA 5

 Product Gene Name   

anti-ITGB5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147561
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    P1F6
 Host    Mouse
 Species Reactivity    Chicken
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 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 1.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.1% Sodium Azide (NaN3)
Preparation
 Immunogen    Human UCLA P3 cells (lung carcinoma).
Buffer Solution
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-ITGB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ITGB5 antibody   

Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

 Application Notes for anti-ITGB5 antibody    Immunohistology: For use on human carcinomas, normal epithelium and keratinocytes using acetone or paraformaldehyde fixed tissue sections.
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NCBI/Uniprot data below describe general gene information for ITGB5. It may not necessarily be applicable to this product.
 NCBI GI #    20127446
 NCBI GeneID    3693
 NCBI Accession #    NP_002204.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002213.4 [Other Products]
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 UniProt Secondary Accession #    B0LPF8; B2RD70 [Other Products]
 UniProt Related Accession #    P18084 [Other Products]
 Molecular Weight    88,054 Da [Similar Products]
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 NCBI Official Full Name    integrin beta-5
 NCBI Official Synonym Full Names    integrin, beta 5
 NCBI Official Symbol    ITGB5 [Similar Products]
 NCBI Protein Information    integrin beta-5
 UniProt Protein Name    Integrin beta-5
 Protein Family    Integrin
 UniProt Gene Name    ITGB5 [Similar Products]
 UniProt Entry Name    ITB5_HUMAN
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 UniProt Comments for ITGB5    ITGB5: Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V. Interacts with MYO10. Belongs to the integrin beta chain family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 3q21.2

Cellular Component: focal adhesion; cell surface; leading edge; plasma membrane; phagocytic vesicle; receptor complex

Molecular Function: integrin binding; protein binding; receptor activity

Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; antigen processing and presentation of peptide antigen via MHC class I; muscle contraction; cell-matrix adhesion; transforming growth factor beta receptor signaling pathway; stress fiber formation; antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
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 Research Articles on ITGB5    1. FRMD5 regulates tumor cell motility via a dual pathway involving FRMD5 binding to integrin beta5 tail and to ROCK1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ITGB5 antibodyPathways associated with anti-ITGB5 antibody
 Reference Product  PubMed Publications
 ITGAV antibody  >6 publications with ITGB5 and ITGAV
 ITGA3 antibody  >4 publications with ITGB5 and ITGA3
 ITGA5 antibody  >4 publications with ITGB5 and ITGA5
 PTK2 antibody  >2 publications with ITGB5 and PTK2
 ITGA1 antibody  >1 publications with ITGB5 and ITGA1
 TLN1 antibody  >1 publications with ITGB5 and TLN1
 VTN antibody  >1 publications with ITGB5 and VTN
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway antibodies  Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
Diseases associated with anti-ITGB5 antibodyOrgans/Tissues associated with anti-ITGB5 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with ITGB5 and Inflammation
 Neoplasm Metastasis Antibodies  >2 publications with ITGB5 and Neoplasm Metastasis
 Lung Diseases Antibodies  >2 publications with ITGB5 and Lung Diseases
 Cardiovascular Diseases Antibodies  >1 publications with ITGB5 and Cardiovascular Diseases
 Anemia Antibodies  >1 publications with ITGB5 and Anemia
 Neoplasms, Experimental Antibodies  >1 publications with ITGB5 and Neoplasms, Experimental
 Necrosis Antibodies  >1 publications with ITGB5 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with ITGB5 and Blood
 Uterus Antibodies  >5 publications with ITGB5 and Uterus
 Placenta Antibodies  >4 publications with ITGB5 and Placenta
 Bone Antibodies  >4 publications with ITGB5 and Bone
 Muscle Antibodies  >4 publications with ITGB5 and Muscle
 Embryonic Tissue Antibodies  >3 publications with ITGB5 and Embryonic Tissue
 Bone Marrow Antibodies  >3 publications with ITGB5 and Bone Marrow
 Vascular Antibodies  >3 publications with ITGB5 and Vascular
 Ovary Antibodies  >3 publications with ITGB5 and Ovary
 Intestine Antibodies  >2 publications with ITGB5 and Intestine
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