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anti-IP10 antibody :: Mouse IP10 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS851299
Unit / Price
0.1 mg  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IP10, Monoclonal Antibody

 Also Known As   

IP10(CXCL10) Antibody

 Product Gene Name   

anti-IP10 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147310
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 Clonality    Monoclonal
 Isotype    IgG2b
 Host    Mouse
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 Specificity    Anti-CXCL10 recognizes recombinant protein CXCL10.
 Form/Format    Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
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 Source Note    Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein CXCL10 as immunogen.
 Immunogen    Recombinant protein corresponding to full length CXCL10.
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 Preparation and Storage    The antibody may be stored at -20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
 Other Notes    Small volumes of anti-IP10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-IP10 antibody    Plant antibody
 Applications Tested/Suitable for anti-IP10 antibody   

ELISA (EIA), Western Blot (WB-Re), Immunohistochemistry (IHC)

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 Western Blot of anti-IP10 antibody    WB (1:1000) analysis of recombinant protein CXCL10 with Anti-CXCLIO.
anti-IP10 antibody Western Blot (WB) image
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 Immunohistochemistry of anti-IP10 antibody    IHC (1:10) to human liver tissue.
anti-IP10 antibody Immunohistochemistry (IHC) image
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NCBI/Uniprot data below describe general gene information for IP10. It may not necessarily be applicable to this product.
 NCBI GI #    149999382
 NCBI GeneID    3627
 NCBI Accession #    NP_001556.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001565.2 [Other Products]
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 UniProt Secondary Accession #    Q96QJ5 [Other Products]
 UniProt Related Accession #    P02778 [Other Products]
 Molecular Weight    10,881 Da
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 NCBI Official Full Name    C-X-C motif chemokine 10
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 10
 NCBI Official Symbol    CXCL10 [Similar Products]
 NCBI Official Synonym Symbols   
C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 10; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10
 UniProt Protein Name    C-X-C motif chemokine 10
 UniProt Synonym Protein Names   
10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10Cleaved into the following chain:CXCL10(1-73)
 UniProt Gene Name    CXCL10 [Similar Products]
 UniProt Synonym Gene Names    INP10; SCYB10; Gamma-IP10; IP-10 [Similar Products]
 UniProt Entry Name    CXL10_HUMAN
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 NCBI Summary for IP10    This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]
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 UniProt Comments for IP10    CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Chemokine; Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: heparin binding; protein binding; CXCR3 chemokine receptor binding; chemokine activity; cAMP-dependent protein kinase regulator activity; receptor binding

Biological Process: muscle development; blood circulation; protein secretion; positive regulation of leukocyte chemotaxis; positive regulation of cAMP metabolic process; chemotaxis; signal transduction; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; cell surface receptor linked signal transduction; response to vitamin D; cell-cell signaling; positive regulation of cell proliferation; response to gamma radiation; positive regulation of transcription from RNA polymerase II promoter; immune response; response to cold; positive regulation of release of sequestered calcium ion into cytosol; regulation of protein kinase activity; negative regulation of myoblast differentiation; inflammatory response; defense response to virus
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 Research Articles on IP10    1. Studied the levels of serum IP-10 and TB antigen-dependent IP-10 at the time of diagnosis and after completing treatment in 32 patients with active TB.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IP10 antibodyPathways associated with anti-IP10 antibody
 Reference Product  PubMed Publications
 CXCL9 antibody  >882 publications with IP10 and CXCL9
 CXCR3 antibody  >804 publications with IP10 and CXCR3
 CCL5 antibody  >627 publications with IP10 and CCL5
 CXCL11 antibody  >448 publications with IP10 and CXCL11
 CCR5 antibody  >169 publications with IP10 and CCR5
 CCL20 antibody  >105 publications with IP10 and CCL20
 CCL11 antibody  >98 publications with IP10 and CCL11
 CXCR2 antibody  >50 publications with IP10 and CXCR2
 CCR3 antibody  >47 publications with IP10 and CCR3
 CCR1 antibody  >46 publications with IP10 and CCR1
 Products by Pathway  Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
Diseases associated with anti-IP10 antibodyOrgans/Tissues associated with anti-IP10 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1113 publications with IP10 and Inflammation
 Necrosis Antibodies  >648 publications with IP10 and Necrosis
 Lung Diseases Antibodies  >318 publications with IP10 and Lung Diseases
 Liver Diseases Antibodies  >220 publications with IP10 and Liver Diseases
 Cardiovascular Diseases Antibodies  >161 publications with IP10 and Cardiovascular Diseases
 Fibrosis Antibodies  >123 publications with IP10 and Fibrosis
 Neoplasms, Experimental Antibodies  >110 publications with IP10 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >83 publications with IP10 and Kidney Diseases
 Lung Injury Antibodies  >61 publications with IP10 and Lung Injury
 Pneumonia Antibodies  >59 publications with IP10 and Pneumonia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1956 publications with IP10 and Blood
 Lung Antibodies  >434 publications with IP10 and Lung
 Liver Antibodies  >258 publications with IP10 and Liver
 Kidney Antibodies  >173 publications with IP10 and Kidney
 Lymph Node Antibodies  >154 publications with IP10 and Lymph Node
 Muscle Antibodies  >117 publications with IP10 and Muscle
 Intestine Antibodies  >87 publications with IP10 and Intestine
 Nerve Antibodies  >58 publications with IP10 and Nerve
 Uterus Antibodies  >33 publications with IP10 and Uterus
 Placenta Antibodies  >28 publications with IP10 and Placenta
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