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anti-IL17 antibody :: Mouse anti-Mouse Interleukin 17 (IL17) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2090634
Western Blot (WB)
Unit / Price
0.01 mg  /  $100 +1 FREE 8GB USB
0.02 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $140 +1 FREE 8GB USB
0.1 mg  /  $175 +1 FREE 8GB USB
0.2 mg  /  $225 +1 FREE 8GB USB
1 mg  /  $505 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 17 (IL17), Monoclonal Antibody

 Also Known As   

Monoclonal Antibody to Interleukin 17 (IL17)

 Product Synonym Names    IL17A; CTLA8; IL-17A; Cytotoxic T-Lymphocyte-Associated Protein 8
 Product Gene Name   

anti-IL17 antibody

[Similar Products]
 Matching Pairs    Antibody: Interleukin 17 (IL17) Clone #C8 (MBS2090634)
Antigen: Interleukin 17 (MBS2030102)
 Matching Pairs    Unconjugated Antibody: Interleukin 17 (IL17) Clone #C8 (MBS2090634)
Biotin Conjugated Secondary Antibody: IgG (MBS2086030)
 Matching Pairs    Unconjugated Antibody: Interleukin 17 (IL17) Clone #C8 (MBS2090634)
FITC Conjugated Secondary Antibody: IgG (MBS2086031)
 Matching Pairs    Unconjugated Antibody: Interleukin 17 (IL17) Clone #C8 (MBS2090634)
Biotin Conjugated Secondary Antibody: IgG (MBS2086033)
 Matching Pairs    Unconjugated Antibody: Interleukin 17 (IL17) Clone #C8 (MBS2090634)
FITC Conjugated Secondary Antibody: IgG (MBS2086034)
 Matching Pairs    Unconjugated Antibody: Interleukin 17 (IL17) Clone #C8 (MBS2090634)
HRP Conjugated Secondary Antibody: IgG (MBS2086035)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q62386
 Clonality    Monoclonal
 Isotype    IgG2a Kappa
 Clone Number    C8
 Host    Mouse
 Species Reactivity    Mouse
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 Specificity    The antibody is a mouse monoclonal antibody raised against IL17. It has been selected for its ability to recognize IL17 in immunohistochemical staining and western blotting.
 Purity/Purification    Protein A + Protein G affinity chromatography
 Form/Format    Liquid
 Concentration    1mg/mL (lot specific)
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 Immunogen    Recombinant Interleukin 17 (IL17)
 Buffer Formulation    0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-IL17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL17 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

 Application Notes for anti-IL17 antibody    Western Blot: 0.5-5ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
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 Western Blot (WB) of anti-IL17 antibody    (Figure. Western Blot; Sample: Recombinant IL17, Mouse.)
anti-IL17 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for IL17. It may not necessarily be applicable to this product.
 NCBI GI #    6754324
 NCBI GeneID    16171
 NCBI Accession #    NP_034682.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_010552.3 [Other Products]
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 UniProt Primary Accession #    Q62386 [Other Products]
 UniProt Secondary Accession #    Q60971 [Other Products]
 UniProt Related Accession #    Q62386 [Other Products]
 Molecular Weight    17,490 Da
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 NCBI Official Full Name    interleukin-17A
 NCBI Official Synonym Full Names    interleukin 17A
 NCBI Official Symbol    Il17a [Similar Products]
 NCBI Official Synonym Symbols   
Il17; Ctla8; IL-17; Ctla-8; IL-17A
[Similar Products]
 NCBI Protein Information    interleukin-17A
 UniProt Protein Name    Interleukin-17A
 UniProt Synonym Protein Names   
Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8
 UniProt Gene Name    Il17a [Similar Products]
 UniProt Synonym Gene Names    Ctla8; Il17; IL-17; IL-17A; CTLA-8 [Similar Products]
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 NCBI Summary for IL17    This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]
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 UniProt Comments for IL17    IL17A: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1|1 A4

Cellular Component: cytoplasm; external side of plasma membrane; extracellular region; extracellular space

Molecular Function: cytokine activity

Biological Process: defense response to fungus; inflammatory response; positive regulation of interleukin-23 production; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter
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 Research Articles on IL17    1. these results demonstrate an important role of CXCR6 in the regulation of pathological Th17 and IL-17A(+)TCRgammadelta(+) T-cell recruitment into atherosclerotic lesions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-IL17 antibodyDiseases associated with anti-IL17 antibody
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1782 publications with IL17 and Inflammation
 Autoimmune Diseases Antibodies  >1474 publications with IL17 and Autoimmune Diseases
 Necrosis Antibodies  >738 publications with IL17 and Necrosis
 Nervous System Diseases Antibodies  >563 publications with IL17 and Nervous System Diseases
 Respiratory Tract Diseases Antibodies  >497 publications with IL17 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >436 publications with IL17 and Lung Diseases
 Central Nervous System Diseases Antibodies  >435 publications with IL17 and Central Nervous System Diseases
 Hypersensitivity Antibodies  >376 publications with IL17 and Hypersensitivity
 Liver Diseases Antibodies  >127 publications with IL17 and Liver Diseases
 Fibrosis Antibodies  >113 publications with IL17 and Fibrosis
Organs/Tissues associated with anti-IL17 antibody
 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >81 publications with IL17 and Thymus
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