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anti-IL-4 antibody :: Mouse Interleukin-4 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS140008 anti-IL-4 antibody
Unit / Price
0.5 mg  /  $305 +1 FREE 8GB USB
1 mg  /  $455 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-4 (IL-4), Monoclonal Antibody

★Popular Item★
 Also Known As   

Mouse Anti Human Interleukin-4

 Product Synonym Names    IL 4 Antibody; Interleukin-4, Mouse Anti-Human; BCGF; BCDF; B cell stimulating factor; BSF-1; Lymphocyte stimulatory factor 1; IL-4; MGC79402; Binetrakin; Pitrakinra
 Product Gene Name   

anti-IL-4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG2a Purification MethodIon exchange
 Clone Number    NYRhIL4
 Host    Mouse
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 Concentration    1mg/ml in PBS (after reconstitution). (lot specific)
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 Physical Appearance    Sterile Filtered White Lyophilized (freeze-dried) powder.
 Reconstitution    Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
 Immunogen    r.Human IL-4.
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 Preparation and Storage    In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
 Other Notes    Small volumes of anti-IL-4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-IL-4 antibody

   Introduction: IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
 Product Categories/Family for anti-IL-4 antibody    ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine
 Applications Tested/Suitable for anti-IL-4 antibody   


 Application Notes for anti-IL-4 antibody    In direct ELISA, using alkaline phosphatase goat anti-mouse Ig (Jackson Laboratories) 1:10,000 dilution will give 0.3 O.D.
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NCBI/Uniprot data below describe general gene information for IL-4. It may not necessarily be applicable to this product.
 NCBI GI #    55742622
 NCBI GeneID    397225
 NCBI Accession #    NP_999288.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_214123.1 [Other Products]
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 UniProt Secondary Accession #    Q29054; Q8MKE6 [Other Products]
 UniProt Related Accession #    Q04745 [Other Products]
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 NCBI Official Full Name    interleukin-4
 NCBI Official Symbol    IL4 [Similar Products]
 NCBI Protein Information    interleukin-4; B-cell stimulatory factor 1; BSF-1; IL-4; lymphocyte stimulatory factor 1
 UniProt Protein Name    Interleukin-4
 UniProt Synonym Protein Names   
B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1
 Protein Family    Interleukin
 UniProt Gene Name    IL4 [Similar Products]
 UniProt Synonym Gene Names    IL-4; BSF-1 [Similar Products]
 UniProt Entry Name    IL4_PIG
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 UniProt Comments for IL-4    Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.
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 Research Articles on IL-4    1. IL-4- and IL-10-producing invariant NKT cells inhibit the Th1 cell response, but not the Th17 cell response
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-IL-4 antibodyDiseases associated with anti-IL-4 antibody
 Products by Pathway  Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >351 publications with IL-4 and Inflammation
 Hypersensitivity Antibodies  >336 publications with IL-4 and Hypersensitivity
 Necrosis Antibodies  >330 publications with IL-4 and Necrosis
 Hypersensitivity, Immediate Antibodies  >272 publications with IL-4 and Hypersensitivity, Immediate
 Asthma Antibodies  >236 publications with IL-4 and Asthma
 Lung Diseases Antibodies  >217 publications with IL-4 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >203 publications with IL-4 and Respiratory Hypersensitivity
 Autoimmune Diseases Antibodies  >174 publications with IL-4 and Autoimmune Diseases
 Liver Diseases Antibodies  >59 publications with IL-4 and Liver Diseases
 Rhinitis Antibodies  >49 publications with IL-4 and Rhinitis
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