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anti-IL6 antibody :: Mouse anti-Rat Interleukin 6 (IL6) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2090592
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $115 +1 FREE 8GB USB
0.05 mg  /  $150 +1 FREE 8GB USB
0.1 mg  /  $190 +1 FREE 8GB USB
0.2 mg  /  $245 +1 FREE 8GB USB
1 mg  /  $555 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 6 (IL6), Monoclonal Antibody

 Also Known As   

Monoclonal Antibody to Interleukin 6 (IL6)

 Product Synonym Names    MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor
 Product Gene Name   

anti-IL6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P20607
 Clonality    Monoclonal
 Isotype    IgG2b Kappa
 Clone Number    C3
 Host    Mouse
 Species Reactivity    Rat
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 Specificity    The antibody is a mouse monoclonal antibody raised against IL6. It has been selected for its ability to recognize IL6 in immunohistochemical staining and western blotting.
 Purity/Purification    Protein A + Protein G affinity chromatography
 Form/Format    Liquid
 Concentration    1mg/mL (lot specific)
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 Immunogen    Eukaryotic Interleukin 6 (IL6)
 Buffer Formulation    0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-IL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL6 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

 Application Notes for anti-IL6 antibody    Western Blot: 0.5-5ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
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 Western Blot (WB) of anti-IL6 antibody    (Figure. Western Blot; Sample: Recombinant IL6, Rat.)
anti-IL6 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-IL6 antibody    (Figure. DAB staining on IHC-P; Samples: Rat Heart Tissue.)
anti-IL6 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-IL6 antibody    (Figure. DAB staining on IHC-P; Samples: Rat Lung Tissue.)
anti-IL6 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IL6. It may not necessarily be applicable to this product.
 NCBI GI #    7549769
 NCBI GeneID    24498
 NCBI Accession #    NP_036721.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012589.2 [Other Products]
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 UniProt Primary Accession #    P20607 [Other Products]
 UniProt Related Accession #    P20607 [Other Products]
 Molecular Weight    24,357 Da
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 NCBI Official Full Name    interleukin-6
 NCBI Official Synonym Full Names    interleukin 6
 NCBI Official Symbol    Il6 [Similar Products]
 NCBI Official Synonym Symbols   
ILg6; Ifnb2
[Similar Products]
 NCBI Protein Information    interleukin-6
 UniProt Protein Name    Interleukin-6
 Protein Family    Interleukin
 UniProt Gene Name    Il6 [Similar Products]
 UniProt Synonym Gene Names    Il-6; IL-6 [Similar Products]
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 NCBI Summary for IL6    a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 2006]
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 UniProt Comments for IL6    Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().
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 Research Articles on IL6    1. Administration of Methylglyoxal led to depletion of antioxidant enzymes, induction of fibrosis (p < 0.001), up-regulated expression of RAGE (3.5 fold), TGF-beta (4.4 fold), SMAD2 (3.7 fold), SMAD3 (6.0 fold), IL-6 (4.3 fold) and TNF-alpha (5.5 fold) in the heart tissues compared to control rats.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL6 antibodyPathways associated with anti-IL6 antibody
 Reference Product  PubMed Publications
 Tnf antibody  >1112 publications with IL6 and Tnf
 Crp antibody  >354 publications with IL6 and Crp
 Stat3 antibody  >258 publications with IL6 and Stat3
 Rela antibody  >43 publications with IL6 and Rela
 Il6st antibody  >38 publications with IL6 and Il6st
 Fos antibody  >36 publications with IL6 and Fos
 Il12b antibody  >28 publications with IL6 and Il12b
 Nfkb1 antibody  >23 publications with IL6 and Nfkb1
 Csf2 antibody  >18 publications with IL6 and Csf2
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-IL6 antibodyOrgans/Tissues associated with anti-IL6 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1701 publications with IL6 and Inflammation
 Necrosis Antibodies  >1307 publications with IL6 and Necrosis
 Autoimmune Diseases Antibodies  >345 publications with IL6 and Autoimmune Diseases
 Arthritis, Rheumatoid Antibodies  >217 publications with IL6 and Arthritis, Rheumatoid
 Atherosclerosis Antibodies  >189 publications with IL6 and Atherosclerosis
 Myocardial Ischemia Antibodies  >182 publications with IL6 and Myocardial Ischemia
 Ischemia Antibodies  >95 publications with IL6 and Ischemia
 Myocardial Infarction Antibodies  >84 publications with IL6 and Myocardial Infarction
 Hypersensitivity Antibodies  >82 publications with IL6 and Hypersensitivity
 Diabetes Mellitus, Type 2 Antibodies  >79 publications with IL6 and Diabetes Mellitus, Type 2
 Organ/Tissue Name  Pubmed Publications
 Uncharacterized Tissue Antibodies  >1 publications with IL6 and Uncharacterized Tissue
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