Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow IL6 rightarrow Monoclonal IL6  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Liver glycogen (LGC) ELISA Kit
 • OTU domain containing 7B (OTUD7B) Antibody
 • IgG4 Antibody
 • COX1 Antibody
 • SSB La Native Protein
 • A Disintegrin Like and Metalloproteinase With Thrombospondin... ELISA Kit
 • A Disintegrin And Metalloprotease 9 (ADAM9) ELISA Kit
 • Mucin 5 Subtype B (MUC5B) ELISA Kit
 • IgE ELISA Kit
 • Adenosine Kinase (ADK) Recombinant Protein
 • Biotin (N-A ) Antibody
 • Interleukin 1 (IL-1) ELISA Kit
 • Goat F(ab')2 Anti-Rabbit IgG (H+L chain specific) Secondary Antibody
 • K39 Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-IL6 antibody :: Mouse anti-Sheep Interleukin 6 (IL6) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2090749 anti-IL6 antibody
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $220 +1 FREE 8GB USB
0.2 mg  /  $285 +1 FREE 8GB USB
1 mg  /  $675 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 6 (IL6), Monoclonal Antibody

 Also Known As   

Biotin-Linked Monoclonal Antibody to Interleukin 6 (IL6)

 Product Gene Name   

anti-IL6 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Interleukin 6 (IL6) (MBS2012740)
Biotin Conjugated Antibody: Interleukin 6 (IL6) (MBS2090749)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    X04430 mRNA
 3D Structure    ModBase 3D Structure for P05231
Section Bar
 Clonality    Monoclonal
 Host    Mouse
 Species Reactivity    Sheep
Section Bar
 Concentration    500ug/ml (lot specific)
Section Bar
 Conjugation    Biotin
 Immunogen    Gly30~Lys208
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-IL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-IL6 antibody   

Western Blot (WB)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for IL6. It may not necessarily be applicable to this product.
 NCBI GI #    10834984
 NCBI GeneID    3569
 NCBI Accession #    NP_000591.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000600.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P05231 [Other Products]
 UniProt Secondary Accession #    Q9UCU2; Q9UCU3; Q9UCU4 [Other Products]
 UniProt Related Accession #    P05231 [Other Products]
 Molecular Weight    23,718 Da
Table BarTOPTable Bar
 NCBI Official Full Name    interleukin-6 isoform 1
 NCBI Official Synonym Full Names    interleukin 6
 NCBI Official Symbol    IL6 [Similar Products]
 NCBI Official Synonym Symbols   
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
[Similar Products]
 NCBI Protein Information    interleukin-6
 UniProt Protein Name    Interleukin-6
 UniProt Synonym Protein Names   
B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
 Protein Family    Interleukin
 UniProt Gene Name    IL6 [Similar Products]
 UniProt Synonym Gene Names    IFNB2; IL-6; BSF-2; CDF; IFN-beta-2 [Similar Products]
Section Bar
 NCBI Summary for IL6    This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Section Bar
 UniProt Comments for IL6    IL6: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ). An inflammatory articular disorder with systemic- onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis. A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men. Belongs to the IL-6 superfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p15.3

Cellular Component: endoplasmic reticulum lumen; external side of plasma membrane; extracellular region; extracellular space; interleukin-6 receptor complex

Molecular Function: cytokine activity; growth factor activity; interleukin-6 receptor binding; protein binding

Biological Process: acute-phase response; aging; bone remodeling; cell growth; cell redox homeostasis; cellular protein metabolic process; cellular response to nutrient levels; cytokine-mediated signaling pathway; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; defense response to protozoan; defense response to virus; endocrine pancreas development; glucose homeostasis; hepatic immune response; humoral immune response; inflammatory response; lymphocyte costimulation; monocyte chemotaxis; muscle maintenance; negative regulation of apoptosis; negative regulation of bone resorption; negative regulation of cell proliferation; negative regulation of chemokine biosynthetic process; negative regulation of collagen biosynthetic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of cytokine secretion; negative regulation of fat cell differentiation; negative regulation of gluconeogenesis; negative regulation of hormone secretion; negative regulation of membrane potential; negative regulation of muscle organ development; negative regulation of protein kinase activity; neuron projection development; neutrophil apoptosis; neutrophil mediated immunity; platelet activation; positive regulation of acute inflammatory response; positive regulation of apoptosis; positive regulation of B cell activation; positive regulation of cell proliferation; positive regulation of chemokine production; positive regulation of DNA replication; positive regulation of epithelial cell proliferation; positive regulation of immunoglobulin secretion; positive regulation of interleukin-6 production; positive regulation of JAK-STAT cascade; positive regulation of leukocyte chemotaxis; positive regulation of MAPK cascade; positive regulation of NF-kappaB transcription factor activity; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoblast differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein import into nucleus, translocation; positive regulation of protein kinase B signaling; positive regulation of smooth muscle cell proliferation; positive regulation of T cell proliferation; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; positive regulation of translation; positive regulation of transmission of nerve impulse; positive regulation of tyrosine phosphorylation of STAT protein; post-translational protein modification; regulation of angiogenesis; regulation of cell shape; regulation of circadian sleep/wake cycle, non-REM sleep; response to amino acid; response to antibiotic; response to caffeine; response to calcium ion; response to cold; response to drug; response to electrical stimulus; response to glucocorticoid stimulus; response to heat; response to insulin stimulus; response to peptidoglycan; response to yeast

Disease: Arteriovenous Malformations Of The Brain; Inflammatory Bowel Disease 1; Kaposi Sarcoma, Susceptibility To; Rheumatoid Arthritis, Systemic Juvenile
Table BarTOPTable Bar
 Research Articles on IL6    1. The present study suggests that serum IL-6 levels of patients with AD might be higher than those of subjects with MCI and healthy controls.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-IL6 antibodyPathways associated with anti-IL6 antibody
 Reference Product  PubMed Publications
 JUN antibody  >473 publications with IL6 and JUN
 STAT3 antibody  >258 publications with IL6 and STAT3
 IL1B antibody  >202 publications with IL6 and IL1B
 IL6R antibody  >92 publications with IL6 and IL6R
 IL17A antibody  >80 publications with IL6 and IL17A
 STAT1 antibody  >51 publications with IL6 and STAT1
 JAK2 antibody  >45 publications with IL6 and JAK2
 IL6ST antibody  >40 publications with IL6 and IL6ST
 SOCS3 antibody  >38 publications with IL6 and SOCS3
 IL23R antibody  >7 publications with IL6 and IL23R
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-IL6 antibodyOrgans/Tissues associated with anti-IL6 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1748 publications with IL6 and Inflammation
 Necrosis Antibodies  >1343 publications with IL6 and Necrosis
 Autoimmune Diseases Antibodies  >354 publications with IL6 and Autoimmune Diseases
 Arthritis, Rheumatoid Antibodies  >221 publications with IL6 and Arthritis, Rheumatoid
 Atherosclerosis Antibodies  >191 publications with IL6 and Atherosclerosis
 Myocardial Ischemia Antibodies  >185 publications with IL6 and Myocardial Ischemia
 Ischemia Antibodies  >97 publications with IL6 and Ischemia
 Myocardial Infarction Antibodies  >85 publications with IL6 and Myocardial Infarction
 Hypersensitivity Antibodies  >84 publications with IL6 and Hypersensitivity
 Diabetes Mellitus, Type 2 Antibodies  >82 publications with IL6 and Diabetes Mellitus, Type 2
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2370 publications with IL6 and Blood
 Vascular Antibodies  >511 publications with IL6 and Vascular
 Bone Antibodies  >323 publications with IL6 and Bone
 Lung Antibodies  >303 publications with IL6 and Lung
 Brain Antibodies  >283 publications with IL6 and Brain
 Muscle Antibodies  >229 publications with IL6 and Muscle
 Kidney Antibodies  >211 publications with IL6 and Kidney
 Connective Tissue Antibodies  >150 publications with IL6 and Connective Tissue
 Skin Antibodies  >138 publications with IL6 and Skin
 Intestine Antibodies  >93 publications with IL6 and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions