View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-jak2b antibody :: Rabbit JAK2 Monoclonal Antibody Catalog # MBS6008461 Unit / Price 0.1 mL / $800 +1 FREE 8GB USB 5x0.1 mL / $3,420 +4 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name JAK2 (jak2b), Monoclonal Antibody Popular Item Full Product Name JAK2, phosphorylated (Tyr1007) Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2) Product Synonym Names Anti -JAK2, phosphorylated (Tyr1007) Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2) Product Gene Name anti-jak2b antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Chromosome Location Chromosome: 5; NC_007116.5 (69030569..69106033). Location: chromosome: 5 Clonality Monoclonal Isotype IgG Clone Number D15E2 Host Rabbit Species Reactivity Human, Monkey, Mouse, Rat Specificity Recognizes endogenous levels of human Jak2 when phosphorylated at Tyr1007. It can also detect double phosphorylation at Tyr1007 and Tyr1008. Cross-reactivity may be observed with phosphorylated Jak3 and Tyk2. Species Crossreactivity: Monkey, mouse and rat. Purity/Purification SupernatantSupernatant Form/Format Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, <0.02% sodium azide, 50% glycerol. Immunogen Synthetic phosphopeptide corresponding to residues surrounding Tyr1007 of human Jak2. Preparation and Storage May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Other Notes Small volumes of anti-jak2b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-jak2b antibody Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. Product Categories/Family for anti-jak2b antibody Antibodies; Abs to Protein Kinases Applications Tested/Suitable for anti-jak2b antibody Western Blot (WB) Application Notes for anti-jak2b antibody Suitable for use in Western Blot.Dilution: Western Blot: 1:1000. Incubate membrne with diluted antibody in 5% w/v BSA, 1x TBS, 0.1% Tween -20 at 4 degree C with gentle shaking, overnight.Optimal dilutions to be determined by the researcher. Western Blot (WB) of anti-jak2b antibody Western blot analysis of extracts from UT-7 cells, untreated or treated with erythropoietin (EPO; 3 units/ml; 5 min) and from untreated HEL cells, using MBS6008461 (upper) or total Jak2 XP Rabbit mAb (lower). HEL cells contain a V617F activating mutation in Jak2. TOP NCBI/Uniprot data below describe general gene information for jak2b. It may not necessarily be applicable to this product. NCBI GI # 226237500 NCBI GeneID 30298 NCBI Accession # BAH47262.1 [Other Products] TOP NCBI Official Full Name jak2 NCBI Official Synonym Full Names Janus kinase 2b NCBI Official Symbol jak2b [Similar Products] NCBI Official Synonym Symbols jak2; JAK2bCA [Similar Products] NCBI Protein Information tyrosine-protein kinase JAK2; PTK JAK2b; Jak2b kinase; protein tyrosine kinase JAK2b TOP Research Articles on jak2b 1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma signal. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Pathways associated with anti-jak2b antibody Products by Pathway Pathway Diagram Adipocytokine Signaling Pathway antibodies Adipocytokine Signaling Pathway Diagram Adipocytokine Signaling Pathway antibodies Adipocytokine Signaling Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Delta-Notch Signaling Pathway antibodies Delta-Notch Signaling Pathway Diagram EGFR1 Signaling Pathway antibodies EGFR1 Signaling Pathway Diagram EPO Receptor Signaling Pathway antibodies EPO Receptor Signaling Pathway Diagram Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram Growth Hormone Receptor Signaling Pathway antibodies Growth Hormone Receptor Signaling Pathway Diagram Hemostasis Pathway antibodies Hemostasis Pathway Diagram Herpes Simplex Infection Pathway antibodies Herpes Simplex Infection Pathway Diagram TOP © 2006-24 MyBioSource.com. 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