View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-jak2b antibody :: Rabbit Jak2, Tyr1007, Tyr1008 Monoclonal Antibody Catalog # MBS601530 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Jak2, Tyr1007, Tyr1008 (jak2b), Monoclonal Antibody Full Product Name Jak2, phosphorylated, Tyr1007, Tyr1008 Product Synonym Names Anti -Jak2, phosphorylated, Tyr1007, Tyr1008 Product Gene Name anti-jak2b antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Chromosome Location Chromosome: 5; NC_007116.5 (69030569..69106033). Location: chromosome: 5 Clonality Monoclonal Isotype IgG Clone Number 6k238 Host Rabbit Species Reactivity Human, Mouse, Rat Specificity Recognizes human JAK2 when phosphorylated at Tyr1007 andTyr1008. Species Crossreactivity: mouse and rat. Purity/Purification SupernatantSupernatant Form/Format Supplied as a liquid 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.01% sodium azide, 0.05% BSA, 40% glycerol.. Immunogen A synthetic phospho-peptide corresponding to residues surrounding Tyr1007 and Tyr1008 of human JAK2 Preparation and Storage May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of anti-jak2b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-jak2b antibody Jak2 is a member of the Janus family tyrosine kinases (Jaks), whose function is to transduce extracellular signals from cytokines and interferons. Jaks associate with cytokine receptors; upon ligand binding, Jaks phosphorylate the receptor. The phosphorylated receptors are bound by SH2-containing proteins, one class of which is the signal transducers and activators of transcription (STATs). Activated STATs, then, translocate to the nucleus to mediate gene transcription (1,2). Tyr1007/1008 of Jak2 are the homologous Tyr1054/1055 in Tyk2, and phosphorylation at these residues is needed for Tyk2 activation (3). A chromosomal aberration involving Jak2 is found in a form of pre-B acute myeloid leukemia (4). Product Categories/Family for anti-jak2b antibody Antibodies; Abs to Tyrosine Kinases Applications Tested/Suitable for anti-jak2b antibody Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC) Application Notes for anti-jak2b antibody Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry.Dilution: Western Blot: 1:5000-1:10,000Immunohistochemistry: 1:50-1:100Immunocytochemistry: 1:50-1:100Immunoprecipitation: 1:50 Western Blot (WB) of anti-jak2b antibody Western blot analysis of immunoprecipitation pellets from Jurkat cell lysate +GM-CSF Immunohistochemistry (IHC) of anti-jak2b antibody Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma using MBS601530. Testing Data of anti-jak2b antibody Dot Blot analysis on immunogen phospho-peptide (A) and non-phospho peptide (B) using MBS601530. TOP NCBI/Uniprot data below describe general gene information for jak2b. It may not necessarily be applicable to this product. NCBI GI # 226237500 NCBI GeneID 30298 NCBI Accession # BAH47262.1 [Other Products] TOP NCBI Official Full Name jak2 NCBI Official Synonym Full Names Janus kinase 2b NCBI Official Symbol jak2b [Similar Products] NCBI Official Synonym Symbols jak2; JAK2bCA [Similar Products] NCBI Protein Information tyrosine-protein kinase JAK2; PTK JAK2b; Jak2b kinase; protein tyrosine kinase JAK2b TOP Research Articles on jak2b 1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma signal. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Pathways associated with anti-jak2b antibody Products by Pathway Pathway Diagram Adipocytokine Signaling Pathway antibodies Adipocytokine Signaling Pathway Diagram Adipocytokine Signaling Pathway antibodies Adipocytokine Signaling Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Delta-Notch Signaling Pathway antibodies Delta-Notch Signaling Pathway Diagram EGFR1 Signaling Pathway antibodies EGFR1 Signaling Pathway Diagram EPO Receptor Signaling Pathway antibodies EPO Receptor Signaling Pathway Diagram Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram Growth Hormone Receptor Signaling Pathway antibodies Growth Hormone Receptor Signaling Pathway Diagram Hemostasis Pathway antibodies Hemostasis Pathway Diagram Herpes Simplex Infection Pathway antibodies Herpes Simplex Infection Pathway Diagram TOP © 2006-24 MyBioSource.com. 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