View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Rabbit anti-Human, Mouse Jak3 Phosphorylated Tyr980/981 Monoclonal Antibody Catalog # MBS605729 Unit / Price 0.02 mL / $520 +1 FREE 8GB USB 0.1 mL / $870 +1 FREE 8GB USB 5x0.1 mL / $3,750 +4 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Jak3 Phosphorylated Tyr980/981, Monoclonal Antibody Full Product Name Jak3 Phosphorylated Tyr980/981 (Janus Kinase 3, EC 2.7.10.2, JAKL, Leukocyte Janus Kinase, LJAK) Product Synonym Names Anti -Jak3 Phosphorylated Tyr980/981 (Janus Kinase 3, EC 2.7.10.2, JAKL, Leukocyte Janus Kinase, LJAK) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG Clone Number 10g85 Host Rabbit Species Reactivity Human, Mouse Specificity Recognizes endogenous levels of Jak3 when phosphorylated at Tyr980/981. Some reactivity may exist with single phosphorylation at these sites. Species crossreactivity Purity/Purification SupernatantSupernatant Form/Format Supplied as a liquid in 10mM sodium HEPES pH 7.5, 150mM NaCl, 0.1mg/ml BSA, 0.02% sodium azide, 50% glycerol. Immunogen Synthetic phosphopeptide corresponding to a region surrounding Tyr980/981 of human and mouse Jak3 protein. Preparation and Storage May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of anti-Jak3 Phosphorylated Tyr980/981 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-Jak3 Phosphorylated Tyr980/981 antibody Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. Product Categories/Family for anti-Jak3 Phosphorylated Tyr980/981 antibody Antibodies; Abs to Protein Kinases Applications Tested/Suitable for anti-Jak3 Phosphorylated Tyr980/981 antibody Western Blot (WB) Application Notes for anti-Jak3 Phosphorylated Tyr980/981 antibody Suitable for use in Western Blot.Dilution: Western Blot: 1:1000 Western Blot (WB) of anti-Jak3 Phosphorylated Tyr980/981 antibody Western blot analysis of extracts from NK-92 cells, untreated or treated with Human Interleukin-2 (hIL-2) (10 ng/ml, 15 minutes), using MBS605729 (upper) or Jak3 Antibody (lower). TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP