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anti-JUND antibody :: Mouse JunD Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS606800 anti-JUND antibody
Unit / Price
0.1 mg  /  $630 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

JunD, Monoclonal Antibody

 Also Known As   

JunD (Jun D proto-oncogene, AP-1, Transcription factor jun-D)

 Product Synonym Names    Anti -JunD (Jun D proto-oncogene, AP-1, Transcription factor jun-D)
 Product Gene Name   

anti-JUND antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (18390563..18392432, complement). Location: 19p13.2
 OMIM    165162
 3D Structure    ModBase 3D Structure for P17535
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    9H99
 Host    Mouse
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 Specificity    Recognizes human/mouse JunD at ~45kD.
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
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 Immunogen    Recombinant human JunD, aa47-156; P17535 (E. coli).
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 Preparation and Storage    Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-JUND antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-JUND antibody

   JunD is a member of the Jun family of nuclear transcription factors. It dimerizes with other Jun or
 Product Categories/Family for anti-JUND antibody    Antibodies; Abs to Transcription Factors
 Applications Tested/Suitable for anti-JUND antibody   

Western Blot (WB)

 Application Notes for anti-JUND antibody    Suitable for use in Western Blot.
Dilution: Western Blot: 1ug/ml
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NCBI/Uniprot data below describe general gene information for JUND. It may not necessarily be applicable to this product.
 NCBI GI #    34019
 NCBI GeneID    3727
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 UniProt Primary Accession #    P17535 [Other Products]
 UniProt Secondary Accession #    Q53EK9 [Other Products]
 UniProt Related Accession #    P17535 [Other Products]
 Molecular Weight    35,174 Da [Similar Products]
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 NCBI Official Full Name    junD protein
 NCBI Official Synonym Full Names    jun D proto-oncogene
 NCBI Official Symbol    JUND [Similar Products]
 NCBI Official Synonym Symbols   
AP-1
[Similar Products]
 NCBI Protein Information    transcription factor jun-D; JunD-FL isoform; activator protein 1
 UniProt Protein Name    Transcription factor jun-D
 Protein Family    Transcription factor
 UniProt Gene Name    JUND [Similar Products]
 UniProt Entry Name    JUND_HUMAN
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 NCBI Summary for JUND    The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. [provided by RefSeq]
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 UniProt Comments for JUND    JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily.

Protein type: Transcription factor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleoplasm; protein complex; chromatin; nucleus

Molecular Function: ligand-dependent nuclear receptor binding; protein binding; enzyme binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity

Biological Process: circadian rhythm; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; response to peptide hormone stimulus; response to light stimulus; positive regulation of osteoblast differentiation; response to mechanical stimulus; positive regulation of transcription from RNA polymerase II promoter; response to lipopolysaccharide; response to organic cyclic substance; aging; osteoblast development
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 Research Articles on JUND    1. These results suggest that the induction of MMP-7 by Tax is regulated by JunD and that MMP-7 could facilitate visceral invasion in adult T-cell leukemia .
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-JUND antibodyPathways associated with anti-JUND antibody
 Reference Product  PubMed Publications
 FOS antibody  >479 publications with JUND and FOS
 FOSB antibody  >163 publications with JUND and FOSB
 MEN1 antibody  >42 publications with JUND and MEN1
 FOSL2 antibody  >34 publications with JUND and FOSL2
 SMAD3 antibody  >17 publications with JUND and SMAD3
 MAPK3 antibody  >12 publications with JUND and MAPK3
 MAPK8 antibody  >11 publications with JUND and MAPK8
 MAPK1 antibody  >11 publications with JUND and MAPK1
 SMAD4 antibody  >9 publications with JUND and SMAD4
 NFE2L2 antibody  >8 publications with JUND and NFE2L2
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies  Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram
Diseases associated with anti-JUND antibodyOrgans/Tissues associated with anti-JUND antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >228 publications with JUND and Neoplasms
 Carcinoma Antibodies  >60 publications with JUND and Carcinoma
 Leukemia Antibodies  >51 publications with JUND and Leukemia
 Cell Transformation, Neoplastic Antibodies  >47 publications with JUND and Cell Transformation, Neoplastic
 Necrosis Antibodies  >43 publications with JUND and Necrosis
 Inflammation Antibodies  >34 publications with JUND and Inflammation
 Adenocarcinoma Antibodies  >31 publications with JUND and Adenocarcinoma
 Endocrine Gland Neoplasms Antibodies  >30 publications with JUND and Endocrine Gland Neoplasms
 Lymphoma Antibodies  >27 publications with JUND and Lymphoma
 Leukemia, T-Cell Antibodies  >27 publications with JUND and Leukemia, T-Cell
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >101 publications with JUND and Blood
 Brain Antibodies  >89 publications with JUND and Brain
 Bone Antibodies  >56 publications with JUND and Bone
 Liver Antibodies  >48 publications with JUND and Liver
 Muscle Antibodies  >40 publications with JUND and Muscle
 Lung Antibodies  >33 publications with JUND and Lung
 Skin Antibodies  >31 publications with JUND and Skin
 Vascular Antibodies  >26 publications with JUND and Vascular
 Kidney Antibodies  >21 publications with JUND and Kidney
 Prostate Antibodies  >18 publications with JUND and Prostate
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