Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow KIF2C rightarrow Monoclonal KIF2C  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • follicle-stimulating hormone (FSH-AB) ELISA Kit
 • Caspase 9 (CASP9) ELISA Kit
 • N-Acetyl Beta-D-Glucosaminidase (NAGase) ELISA Kit
 • Adrenergic Receptor B2 (Phospho-Ser355+Ser356) (ADRB2) Antibody
 • sVCAM-1 ELISA Kit
 • ProMatrix Metalloproteinase-9 (ProMMP 9) Recombinant Protein
 • 2,3 Diphosphoglycerate (2,3-DPG) ELISA Kit
 • MLL4 Antibody
 • Laminin subunit gamma-1 (LAMC1), partial Recombinant Protein
 • IGFBP-1 ELISA Kit
 • Serum Albumin (SA) ELISA Kit
 • CHD3 ELISA Kit
 • Syndecan-1-CD138 (SDC1-CD138) ELISA Kit
 • Negative Control siRNA Negative Control
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-KIF2C antibody :: Mouse anti-Human KIF2C Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120222
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KIF2C, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human KIF2C

 Product Synonym Names    Homo sapiens kinesin family member 2C (KIF2C); MCAK; KNSL6
 Product Gene Name   

anti-KIF2C antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    604538
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2488C3a
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Concentration    100 ug/ml (1.0 ml) (lot specific)
Section Bar
 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
Section Bar
 Other Notes    Small volumes of anti-KIF2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-KIF2C antibody

   The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-KIF2C antibody   

Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)

Section Bar
 Quality Control of anti-KIF2C antibody    Western blot analysis of immunized recombinant protein, using anti-KIF2C monoclonal antibody.
anti-KIF2C antibody Quality Control image
Section Bar
 Quality Control #2 of anti-KIF2C antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-KIF2C antibody Quality Control #2 image
Section Bar
 Western Blot (WB) of anti-KIF2C antibody    Detection of human KIF2C by Western blot.

Samples: Whole cell lysate (25 ug) from HeLa cells. [Lot No. 2488C3a-1]

Predicted molecular weight: 81 kDa
anti-KIF2C antibody Western Blot (WB) (WB) image
Section Bar
 Flow Cytometry (FC/FACS) of anti-KIF2C antibody    HeLa cells were fixed in 2% paraformaldehyde/PBS and then permeabilized in 90% methanol. Cells were stained with anti-KIF2C mAb (shaded) or isotype control (unshaded) followed by Alexa Fluor(R) 488-conjugated goat anti-mouse IgG. [Lot No. 2488C3a-1]
anti-KIF2C antibody Flow Cytometry (FC/FACS) (FC/FACS) image
Section Bar
 Immunocytochemistry (ICC) of anti-KIF2C antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-KIF2C mAb. Nuclear was stained with Hoechst (blue fluorescence).[Lot No. 2488C3a-1]
anti-KIF2C antibody Immunocytochemistry (ICC) (ICC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for KIF2C. It may not necessarily be applicable to this product.
 NCBI GI #    166795249
 NCBI GeneID    11004
 NCBI Accession #    NP_006836.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006845 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q9BWV8; B3ITR9 [Other Products]
 UniProt Related Accession #    Q99661 [Other Products]
 Molecular Weight    75,561 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens kinesin family member 2C (KIF2C), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    kinesin family member 2C
 NCBI Official Symbol    KIF2C [Similar Products]
 NCBI Official Synonym Symbols   
MCAK; CT139; KNSL6
[Similar Products]
 NCBI Protein Information    kinesin-like protein KIF2C; kinesin-like protein 6; mitotic centromere-associated kinesin
 UniProt Protein Name    Kinesin-like protein KIF2C
 UniProt Synonym Protein Names   
Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK
 Protein Family    Kinesin-like protein
 UniProt Gene Name    KIF2C [Similar Products]
 UniProt Entry Name    KIF2C_HUMAN
Section Bar
 NCBI Summary for KIF2C    This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Section Bar
 UniProt Comments for KIF2C    KIF2C: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cancer Testis Antigen (CTA); Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: kinetochore; microtubule cytoskeleton; kinesin complex; membrane; cytoplasmic microtubule; nucleus; cytosol; chromosome, pericentric region

Molecular Function: centromeric DNA binding; microtubule plus-end binding; protein binding; ATPase activity; microtubule motor activity; ATP binding

Biological Process: cell proliferation; mitosis; cell division; metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule depolymerization; regulation of chromosome segregation; mitotic cell cycle; blood coagulation; mitotic metaphase plate congression; microtubule-based movement; establishment and/or maintenance of microtubule cytoskeleton polarity
Table BarTOPTable Bar
 Research Articles on KIF2C    1. this study suggests a new mechanism by which Plk1 regulates MCAK: by regulating its degradation and hence controlling its turnover in mitosis.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-KIF2C antibodyPathways associated with anti-KIF2C antibody
 Reference Product  PubMed Publications
 AURKB antibody  >17 publications with KIF2C and AURKB
 BIRC5 antibody  >8 publications with KIF2C and BIRC5
 BUB1 antibody  >6 publications with KIF2C and BUB1
 CDC20 antibody  >3 publications with KIF2C and CDC20
 CDCA8 antibody  >3 publications with KIF2C and CDCA8
 PLK1 antibody  >3 publications with KIF2C and PLK1
 MAPRE1 antibody  >2 publications with KIF2C and MAPRE1
 CENPA antibody  >1 publications with KIF2C and CENPA
 NDC80 antibody  >1 publications with KIF2C and NDC80
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Kinesins Pathway antibodies  Kinesins Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 MHC Class II Antigen Presentation Pathway antibodies  MHC Class II Antigen Presentation Pathway Diagram
Diseases associated with anti-KIF2C antibodyOrgans/Tissues associated with anti-KIF2C antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with KIF2C and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >3 publications with KIF2C and Cell Transformation, Neoplastic
 Brain Diseases Antibodies  >2 publications with KIF2C and Brain Diseases
 Nervous System Diseases Antibodies  >2 publications with KIF2C and Nervous System Diseases
 Adenocarcinoma Antibodies  >2 publications with KIF2C and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >2 publications with KIF2C and Neoplasms, Experimental
 Prostatic Neoplasms Antibodies  >1 publications with KIF2C and Prostatic Neoplasms
 Atherosclerosis Antibodies  >1 publications with KIF2C and Atherosclerosis
 Lung Neoplasms Antibodies  >1 publications with KIF2C and Lung Neoplasms
 Liver Neoplasms Antibodies  >1 publications with KIF2C and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with KIF2C and Blood
 Lung Antibodies  >4 publications with KIF2C and Lung
 Testis Antibodies  >4 publications with KIF2C and Testis
 Intestine Antibodies  >2 publications with KIF2C and Intestine
 Lymph Node Antibodies  >2 publications with KIF2C and Lymph Node
 Lymph Antibodies  >2 publications with KIF2C and Lymph
 Brain Antibodies  >2 publications with KIF2C and Brain
 Stomach Antibodies  >1 publications with KIF2C and Stomach
 Muscle Antibodies  >1 publications with KIF2C and Muscle
 Liver Antibodies  >1 publications with KIF2C and Liver
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions