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anti-KRT7 antibody :: Mouse anti-Human Keratin 7 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS5306552
Western Blot (WB)
Unit / Price
0.1 mg  /  $430 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Keratin 7 (KRT7), Monoclonal Antibody

★Popular Item★
 Also Known As   

Mouse monoclonal Keratin 7 antibody (N-terminus)

 Product Synonym Names    Keratin 7 antibody (N-terminus), Monoclonal Keratin 7 antibody, Anti-Keratin 7 antibody, Cytokeratin 7 antibody, Cytokeratin-7- antibody, Cytokeratin-7 antibody, Keratin K7 antibody, Cytokeratin 7 antibody
 Product Gene Name   

anti-KRT7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    X03212 mRNA
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    M80511
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Keratin 7 antibody detects endogenous levels Keratin 7 and does not cross-react with related proteins
 Form/Format    Liquid in 0.1M Tris-Glycine, pH 7.4 with 150mM NaCI, 0.2% Sodium Azide, and 50% Glycerol.
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Purified recombinant human Keratin 7 protein fragment expressed in E. coli
 Biological Significance    Antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively.
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 Preparation and Storage    Store at 4C for short term, -20C for long term.
 Other Notes    Small volumes of anti-KRT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-KRT7 antibody    Cell Biology
 Applications Tested/Suitable for anti-KRT7 antibody   

Suitable for use in WB and ICC.

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 Western Blot (WB) of anti-KRT7 antibody    Western blot detection of Keratin 7(N-terminus) antibody in A459&Hela cell lysates using Keratin 7(N-terminus) antibody (1:1000 diluted). Predicted band size: 50KDa Observed band size: 50KDa.
anti-KRT7 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for KRT7. It may not necessarily be applicable to this product.
 NCBI GI #    24753853
 NCBI GeneID    3855
 NCBI Accession #    AAN64035.1 [Other Products]
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 UniProt Secondary Accession #    Q92676; Q9BUD8; Q9Y3R7 [Other Products]
 UniProt Related Accession #    P08729 [Other Products]
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 NCBI Official Full Name    keratin 7
 NCBI Official Synonym Full Names    keratin 7
 NCBI Official Symbol    KRT7 [Similar Products]
 NCBI Official Synonym Symbols   
K7; CK7; SCL; K2C7
[Similar Products]
 NCBI Protein Information    keratin, type II cytoskeletal 7
 UniProt Protein Name    Keratin, type II cytoskeletal 7
 UniProt Synonym Protein Names   
Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7
 Protein Family    Keratin
 UniProt Gene Name    KRT7 [Similar Products]
 UniProt Synonym Gene Names    SCL; CK-7; K7 [Similar Products]
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 NCBI Summary for KRT7    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KRT7    K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding
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 Research Articles on KRT7    1. Survival analysis showed that the non-small cell lung carcinoma patients with enhanced expression of CK7, ELF3, EGFR, and EphB4 mRNA in peripheral blood leukocytes had poorer disease-free survival and overall survival than those without.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-KRT7 antibodyPathways associated with anti-KRT7 antibody
 Reference Product  PubMed Publications
 CDX2 antibody  >29 publications with KRT7 and CDX2
 MUC2 antibody  >19 publications with KRT7 and MUC2
 MUC1 antibody  >14 publications with KRT7 and MUC1
 PIP antibody  >5 publications with KRT7 and PIP
 MME antibody  >1 publications with KRT7 and MME
 SLC4A3 antibody  >1 publications with KRT7 and SLC4A3
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Keratinization Pathway antibodies  Keratinization Pathway Diagram
Diseases associated with anti-KRT7 antibodyOrgans/Tissues associated with anti-KRT7 antibody
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >60 publications with KRT7 and Lung Neoplasms
 Skin Diseases Antibodies  >55 publications with KRT7 and Skin Diseases
 Breast Neoplasms Antibodies  >54 publications with KRT7 and Breast Neoplasms
 Lung Diseases Antibodies  >52 publications with KRT7 and Lung Diseases
 Ovarian Diseases Antibodies  >47 publications with KRT7 and Ovarian Diseases
 Liver Neoplasms Antibodies  >44 publications with KRT7 and Liver Neoplasms
 Kidney Diseases Antibodies  >42 publications with KRT7 and Kidney Diseases
 Carcinoma, Renal Cell Antibodies  >35 publications with KRT7 and Carcinoma, Renal Cell
 Skin Neoplasms Antibodies  >22 publications with KRT7 and Skin Neoplasms
 Fibrosis Antibodies  >18 publications with KRT7 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >87 publications with KRT7 and Liver
 Lung Antibodies  >63 publications with KRT7 and Lung
 Kidney Antibodies  >46 publications with KRT7 and Kidney
 Stomach Antibodies  >45 publications with KRT7 and Stomach
 Bladder Antibodies  >41 publications with KRT7 and Bladder
 Ovary Antibodies  >38 publications with KRT7 and Ovary
 Thyroid Antibodies  >37 publications with KRT7 and Thyroid
 Blood Antibodies  >35 publications with KRT7 and Blood
 Skin Antibodies  >35 publications with KRT7 and Skin
 Intestine Antibodies  >34 publications with KRT7 and Intestine
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