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Rabbit LKB 1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS605267 anti-LKB 1 antibody
Unit / Price
0.1 mL  /  $540 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LKB 1, Monoclonal Antibody

 Also Known As   

LKB 1 (STK11, Serine/Threonine Kinase 11, LKB1, PJS, Renal carcinoma antigen NY-REN-19, Serine/threonine-protein kinase 11, Serine/threonine-protein kinase LKB1)

 Product Synonym Names    Anti -LKB 1 (STK11, Serine/Threonine Kinase 11, LKB1, PJS, Renal carcinoma antigen NY-REN-19, Serine/threonine-protein kinase 11, Serine/threonine-protein kinase LKB1)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG
 Clone Number    7H36
 Host    Rabbit
 Species Reactivity    Human, Monkey, Rat
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 Specificity    Recognizes endogenous levels of human LKB1 protein at ~54kD. Species Crossreactivity: Monkey and rat.
 Purity/Purification    Supernatant
Supernatant
 Form/Format    Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.
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 Immunogen    Synthetic peptide derived from the sequence of human LKB1, conjugated to KLH.
 Positive Control    Caki-1, COS, and insulin treated 293T cell extracts.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-LKB 1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LKB 1 antibody

   LKB1 (STK11) is a serine/threonine kinase and tumor suppressor that helps control cell structure, apoptosis and energy homeostasis through regulation of numerous downstream kinases (1,2). A cytosolic protein complex comprised of LKB1, putative kinase STRAD, and the MO25 scaffold protein, activates both AMP-activated protein kinase (AMPK) and several AMPK-related kinases (3). AMPK plays a predominant role as the master regulator of cellular energy homeostasis, controlling downstream effectors that regulate cell growth and apoptosis in response to cellular ATP concentrations (4). LKB1 appears to be phosphorylated in cells at several sites, including human LKB1 at Ser31/325/428 and Thr189/336/363 (5).
 Product Categories/Family for anti-LKB 1 antibody    Antibodies; Abs to Protein Kinases
 Applications Tested/Suitable for anti-LKB 1 antibody   

Western Blot (WB), Immunoprecipitation (IP)

 Application Notes for anti-LKB 1 antibody    Suitable for use in Immunoprecipitation and Western Blot.
Dilution: Immunoprecipitation: 1:100
Western Blot: 1:1000
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 Molecular Weight    54kD [Similar Products]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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