Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow LMO1 rightarrow Monoclonal LMO1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • S100A10 Antibody
 • NADH-cytochrome b5 reductase 3 (CYB5R3) Antibody
 • ABO Antibody
 • Cannabinoid Receptor 2 (CNR2) Peptide
 • Maltose and Glucose Assay Kit
 • Retinol Binding Protein 4 (RBP4) ELISA Kit
 • PTGDR Antibody
 • Aldosterone 3 Antibody
 • ZNF44 Antibody
 • MACC1 Antibody
 • CT47A Antibody
 • Isocitrate dehydrogenase (ICDH) Antibody
 • SFRP3 (FRZB) Recombinant Protein
 • CLIM1 Antibody
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-LMO1 antibody :: Mouse anti-Human LMO1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120420
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LMO1, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human LMO1

 Product Synonym Names    Homo sapiens LIM domain only 1 (rhombotin 1), mRNA (cDNA clone MGC:116691 IMAGE:40000076), complete cds.; RHOM1; TTG1
 Product Gene Name   

anti-LMO1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    186921
Section Bar
 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    790C2a
 Host    Mouse
 Species Reactivity    Human
Section Bar
 Concentration    100 ug/ml (1.0 ml) (lot specific)
Section Bar
 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
Section Bar
 Other Notes    Small volumes of anti-LMO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for anti-LMO1 antibody

   LMO1 enocdes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.[NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-LMO1 antibody   

Dot Blot (DB), Immunocytochemistry (ICC)

Section Bar
 Quality Control of anti-LMO1 antibody    Western blot analysis of immunized recombinant protein, using anti-LMO1 monoclonal antibody.
anti-LMO1 antibody Quality Control image
Section Bar
 Quality Control #2 of anti-LMO1 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-LMO1 antibody Quality Control #2 image
Section Bar
 Immunocytochemistry (ICC) of anti-LMO1 antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-LMO1 mAb. [Lot No.790C2a-1]
anti-LMO1 antibody Immunocytochemistry (ICC) (ICC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for LMO1. It may not necessarily be applicable to this product.
 NCBI GI #    109730104
 NCBI GeneID    4004
 NCBI Accession #    BC096057 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q4VBC5; Q8IXR0; E9PSF5 [Other Products]
 UniProt Related Accession #    P25800 [Other Products]
 Molecular Weight    17,697 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Homo sapiens LIM domain only 1 (rhombotin 1), mRNA
 NCBI Official Synonym Full Names    LIM domain only 1 (rhombotin 1)
 NCBI Official Symbol    LMO1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    rhombotin-1; LIM domain only protein 1; LMO-1; T-cell translocation gene 1; T-cell translocation protein 1; cysteine-rich protein TTG-1
 UniProt Protein Name    Rhombotin-1
 UniProt Synonym Protein Names   
Cysteine-rich protein TTG-1; LIM domain only protein 1; LMO-1; T-cell translocation protein 1
 Protein Family    Rhombotin
 UniProt Gene Name    LMO1 [Similar Products]
 UniProt Entry Name    RBTN1_HUMAN
Section Bar
 NCBI Summary for LMO1    This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]
Section Bar
 UniProt Comments for LMO1    LMO1: May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p15;q11) with TCRD.

Protein type: DNA-binding; Oncoprotein

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: nucleus

Molecular Function: zinc ion binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
Table BarTOPTable Bar
 Research Articles on LMO1    1. LMO1 is a commonly activated tumor promoter that activates AKT signaling in colorectal cancer and a new predictive marker for targeted therapy.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-LMO1 antibodyDiseases associated with anti-LMO1 antibody
 Reference Product  PubMed Publications
 TAL1 antibody  >27 publications with LMO1 and TAL1
 LDB1 antibody  >8 publications with LMO1 and LDB1
 LYL1 antibody  >8 publications with LMO1 and LYL1
 GATA3 antibody  >7 publications with LMO1 and GATA3
 TAL2 antibody  >2 publications with LMO1 and TAL2
 Disease Name  Pubmed Publications
 Leukemia, T-Cell Antibodies  >43 publications with LMO1 and Leukemia, T-Cell
 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >14 publications with LMO1 and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
 Breast Neoplasms Antibodies  >5 publications with LMO1 and Breast Neoplasms
 Brain Diseases Antibodies  >4 publications with LMO1 and Brain Diseases
 Disease Models, Animal Antibodies  >3 publications with LMO1 and Disease Models, Animal
 Seizures Antibodies  >2 publications with LMO1 and Seizures
 Neoplasms, Experimental Antibodies  >2 publications with LMO1 and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >1 publications with LMO1 and Ovarian Neoplasms
 Abnormalities, Multiple Antibodies  >1 publications with LMO1 and Abnormalities, Multiple
 Neural Tube Defects Antibodies  >1 publications with LMO1 and Neural Tube Defects
Organs/Tissues associated with anti-LMO1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with LMO1 and Brain
 Lung Antibodies  >4 publications with LMO1 and Lung
 Muscle Antibodies  >4 publications with LMO1 and Muscle
 Testis Antibodies  >2 publications with LMO1 and Testis
 Prostate Antibodies  >1 publications with LMO1 and Prostate
 Pancreas Antibodies  >1 publications with LMO1 and Pancreas
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions