View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Rat anti-Mouse LPAM-1 (Integrin alpha 4 beta 7) Monoclonal Antibody Catalog # MBS673623 Unit / Price 0.1 mg / $320 +1 FREE 8GB USB 5x0.1 mg / $1,260 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name LPAM-1 (Integrin alpha 4 beta 7), Monoclonal Antibody Full Product Name Rat Anti-Mouse LPAM-1-PE Product Synonym Names Rat Anti-Mouse LPAM-1 - Phycoerythrin-Labeled; Rat Anti-Mouse LPAM-1 (Integrin alpha 4 beta 7) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype Rat (Fischer) IgG2a kappa Clone Number DATK32 Host Rat Species Reactivity Mouse Specificity Mouse LPAM-1 (Integrin alpha 4 beta 7)The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha 4 beta 7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.1-4 The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer.1 2 Form/Format R - phycoerythrin (R - PE) Conjugate Immunogen AKR/Cum mouse spontaneous T lymphoma cell line TK1 Characterization To ensure lot-to-lot consistency, each batch of product is tested by flow cytometry to conform with characteristics of a standard reference reagent. Preparation and Storage The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed. Other Notes Small volumes of anti-LPAM-1 (Integrin alpha 4 beta 7) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Applications Tested/Suitable for anti-LPAM-1 (Integrin alpha 4 beta 7) antibody Flow Cytometry; Immunohistochemistry (Frozen Sections) Application Notes for anti-LPAM-1 (Integrin alpha 4 beta 7) antibody Research Application(s): Blockade of binding to cell adhesion moleculesInduction of homotypic cellular aggregationFlow Cytometry Suggested Dilution: <=0.1 ug/10^6 cells TOP Product References and Citations for anti-LPAM-1 (Integrin alpha 4 beta 7) antibody 1. Andrew, D. P., C, Berlin, S. Honda, T. Yoshino, et al. 1994. J. Immunol. 153:3847.2. Andrew, D. P., L.S. Rott, P.J. Kilshaw, et al. 1996. Eur J. Immunol. 26:897.3. Hamann, A., et al. 1994. J. Immunol. 152:3282.4. Berlin, C., E.L. Berg, M.J. Briskin, et al. 1993. Cell 74:185. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP