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anti-LRP antibody :: Mouse LRP Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS531812 anti-LRP antibody
Unit / Price
0.05 mg  /  $430 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LRP, Monoclonal Antibody

 Also Known As   

LRP antibody (515 kDa)

 Product Synonym Names    Monoclonal LRP (515 kDa); Anti-LRP (515 kDa); Low Density LPR; LPR/alpha 2MR; Anti LRP (515 kDa); LRP-515antibody; LPR515; Human Liporotein Receptor Related Protein; LRP (515 kDa)
 Product Gene Name   

anti-LRP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605088
 3D Structure    ModBase 3D Structure for Q14764
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    8G1
 Host    Mouse
 Species Reactivity    This antibody reacts with the 515 kDa a-chain of the Human LRP/a2MR which is expressed in a restricted spectrum of cell types
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 Specificity    Human LRP
 Form/Format    Lyophilized. Reconstitute in 1 ml distilled water (final solution contains 0.5% BSA in PBS buffer, pH 7.4)
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 Biological Significance    Lipoprotein receptor-related proteins are a group of human proteins. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91).
 Immunogen    LRP antibody (515 kDa) was raised in mouse using human LRP/a2MR as the immunogen.
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 Preparation and Storage    Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles
 Other Notes    Small volumes of anti-LRP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-LRP antibody

   Mouse monoclonal LRP antibody (515 kDa)
 Product Categories/Family for anti-LRP antibody    Signal Transduction
 Applications Tested/Suitable for anti-LRP antibody   

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-LRP antibody    IHC: 1:20
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NCBI/Uniprot data below describe general gene information for LRP. It may not necessarily be applicable to this product.
 NCBI GI #    19577290
 NCBI Accession #    CAA56256.2 [Other Products]
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 UniProt Primary Accession #    Q14764 [Other Products]
 UniProt Secondary Accession #    Q96BG4; Q9BPW6; Q9BQT1; Q9UBD1 [Other Products]
 Molecular Weight    99,327 Da
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 NCBI Official Full Name    lrp
 UniProt Protein Name    Major vault protein
 UniProt Synonym Protein Names   
Lung resistance-related protein
 Protein Family    Leucine-rich protein
 UniProt Gene Name    MVP [Similar Products]
 UniProt Synonym Gene Names    LRP; MVP [Similar Products]
 UniProt Entry Name    MVP_HUMAN
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 UniProt Comments for LRP    MVP: Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cytoskeleton; membrane; perinuclear region of cytoplasm; cytoplasm; nuclear pore; ribonucleoprotein complex; nucleus

Molecular Function: protein binding; protein phosphatase binding; protein kinase binding

Biological Process: cell proliferation; protein transport; mRNA transport; negative regulation of protein amino acid autophosphorylation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LRP antibodyDiseases associated with anti-LRP antibody
 Reference Product  PubMed Publications
 ABCB1 antibody  >45 publications with LRP and ABCB1
 TEP1 antibody  >20 publications with LRP and TEP1
 PTEN antibody  >8 publications with LRP and PTEN
 TP53 antibody  >4 publications with LRP and TP53
 PTPN11 antibody  >1 publications with LRP and PTPN11
 RFWD2 antibody  >1 publications with LRP and RFWD2
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >782 publications with LRP and Heart Diseases
 Nervous System Diseases Antibodies  >159 publications with LRP and Nervous System Diseases
 Lung Neoplasms Antibodies  >151 publications with LRP and Lung Neoplasms
 Brain Diseases Antibodies  >80 publications with LRP and Brain Diseases
 Fibrosis Antibodies  >32 publications with LRP and Fibrosis
 Disease Models, Animal Antibodies  >32 publications with LRP and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >32 publications with LRP and Neoplasm Metastasis
 Hypertension Antibodies  >32 publications with LRP and Hypertension
 Hypertrophy Antibodies  >30 publications with LRP and Hypertrophy
 Myocardial Infarction Antibodies  >27 publications with LRP and Myocardial Infarction
Organs/Tissues associated with anti-LRP antibody
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >571 publications with LRP and Heart
 Blood Antibodies  >279 publications with LRP and Blood
 Lung Antibodies  >216 publications with LRP and Lung
 Vascular Antibodies  >117 publications with LRP and Vascular
 Brain Antibodies  >84 publications with LRP and Brain
 Muscle Antibodies  >66 publications with LRP and Muscle
 Bone Antibodies  >63 publications with LRP and Bone
 Connective Tissue Antibodies  >45 publications with LRP and Connective Tissue
 Liver Antibodies  >37 publications with LRP and Liver
 Bladder Antibodies  >32 publications with LRP and Bladder
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