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anti-Lif antibody :: Rat Lif Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS668022
Unit / Price
0.025 mg  /  $145 +1 FREE 8GB USB
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lif, Monoclonal Antibody

 Also Known As   

Lif Monoclonal Antibody

 Product Gene Name   

anti-Lif antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P09056
 Clonality    Monoclonal
 Isotype    Rat IgG2b, Kappa
 Clone Number    ABM2C57
 Host    Rat
 Species Reactivity    Mouse (Predicted Reactivity: Mouse
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 Form/Format    Purified (Liquid)
 Concentration    0.5 mg/ml, 200 l (lot specific)
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 Antigen    Lif
 Immunogen    A partial recombinant mouse Lif protein (amino acids 110-203) was used as the immunogen for this antibody
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 Preparation and Storage    Store antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles. Expire 1 year from date of purchase.
 Other Notes    Small volumes of anti-Lif antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-Lif antibody    Misc
 Applications Tested/Suitable for anti-Lif antibody   

Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-Lif antibody    Expression analysis of Mouse Lif. Anti- M.Lif antibody (Clone: no ABM2C57) was used at 3 g/ml on (1) mBrain, (2) 3T3 Lysates
anti-Lif antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-Lif antibody    Immunohistochemical analysis of Lif in mouse brain tissue using Lif antibody (Clone: ABM2C57) at 5 ug/ml.
anti-Lif antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) #2 of anti-Lif antibody    Immunohistochemical analysis of Lif in mouse small intestine tissue using Lif antibody (Clone: ABM2C57) at 5 ug/ml.
anti-Lif antibody Immunohistochemistry (IHC) #2 (IHC) image
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NCBI/Uniprot data below describe general gene information for Lif. It may not necessarily be applicable to this product.
 NCBI GI #    88014736
 NCBI GeneID    16878
 NCBI Accession #    NP_001034626.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001039537.2 [Other Products]
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 UniProt Primary Accession #    P09056 [Other Products]
 UniProt Related Accession #    P09056 [Other Products]
 Molecular Weight    22,287 Da
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 NCBI Official Full Name    leukemia inhibitory factor isoform b
 NCBI Official Synonym Full Names    leukemia inhibitory factor
 NCBI Official Symbol    Lif [Similar Products]
 NCBI Protein Information    leukemia inhibitory factor; d factor; differentiation-stimulating factor; myeloid leukaemia inhibitory factor
 UniProt Protein Name    Leukemia inhibitory factor
 UniProt Synonym Protein Names   
Differentiation-stimulating factor; D factor
 Protein Family    Leukemia inhibitory factor
 UniProt Gene Name    Lif [Similar Products]
 UniProt Synonym Gene Names    LIF; D factor [Similar Products]
 UniProt Entry Name    LIF_MOUSE
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 UniProt Comments for Lif    LIF: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. Belongs to the LIF/OSM family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: growth factor activity; leukemia inhibitory factor receptor binding; cytokine activity; receptor binding

Biological Process: transcription from RNA polymerase II promoter; maternal process involved in pregnancy; leukemia inhibitory factor signaling pathway; negative regulation of hormone secretion; tyrosine phosphorylation of Stat3 protein; decidualization; positive regulation of adrenocorticotropic hormone secretion; positive regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of cell proliferation; astrocyte differentiation; positive regulation of MAPKKK cascade; regulation of cell differentiation; negative regulation of meiosis; positive regulation of cell proliferation; positive regulation of macrophage differentiation; muscle morphogenesis; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of astrocyte differentiation; organ regeneration; stem cell maintenance; stem cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of angiogenesis; positive regulation of tyrosine phosphorylation of Stat1 protein; retina development in camera-type eye; neuron development; blood vessel remodeling; immune response; positive regulation of transcription from RNA polymerase II promoter; alveolus development; embryo implantation; lung development
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 Research Articles on Lif    1. Expression of LIF protects the lung from lung injury and enhanced pathology during respiratory syncytial virus infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Lif antibodyPathways associated with anti-Lif antibody
 Reference Product  PubMed Publications
 Osm antibody  >683 publications with Lif and Osm
 Lifr antibody  >465 publications with Lif and Lifr
 Cntf antibody  >417 publications with Lif and Cntf
 Il6st antibody  >238 publications with Lif and Il6st
 Cntfr antibody  >38 publications with Lif and Cntfr
 Il11ra2 antibody  >8 publications with Lif and Il11ra2
 Csf3 antibody  >4 publications with Lif and Csf3
 Ctf1 antibody  >2 publications with Lif and Ctf1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 ESC Pluripotency Pathways antibodies  ESC Pluripotency Pathways Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 PluriNetWork Pathway antibodies  PluriNetWork Pathway Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram
Diseases associated with anti-Lif antibodyOrgans/Tissues associated with anti-Lif antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >285 publications with Lif and Inflammation
 Necrosis Antibodies  >283 publications with Lif and Necrosis
 Cardiovascular Diseases Antibodies  >191 publications with Lif and Cardiovascular Diseases
 Female Urogenital Diseases Antibodies  >166 publications with Lif and Female Urogenital Diseases
 Infertility, Female Antibodies  >109 publications with Lif and Infertility, Female
 Neoplasms, Experimental Antibodies  >86 publications with Lif and Neoplasms, Experimental
 Heart Diseases Antibodies  >70 publications with Lif and Heart Diseases
 Lung Diseases Antibodies  >70 publications with Lif and Lung Diseases
 Liver Diseases Antibodies  >60 publications with Lif and Liver Diseases
 Breast Neoplasms Antibodies  >46 publications with Lif and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >518 publications with Lif and Bone
 Embryonic Tissue Antibodies  >345 publications with Lif and Embryonic Tissue
 Bone Marrow Antibodies  >249 publications with Lif and Bone Marrow
 Liver Antibodies  >196 publications with Lif and Liver
 Skin Antibodies  >186 publications with Lif and Skin
 Spleen Antibodies  >78 publications with Lif and Spleen
 Thymus Antibodies  >48 publications with Lif and Thymus
 Intestine Antibodies  >34 publications with Lif and Intestine
 Pancreas Antibodies  >28 publications with Lif and Pancreas
 Mammary Gland Antibodies  >17 publications with Lif and Mammary Gland
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