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anti-PNLIP antibody :: Mouse Lipase Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS190314 anti-PNLIP antibody
Unit / Price
0.1 mg  /  $195 +1 FREE 8GB USB
0.5 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $615 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lipase (PNLIP), Monoclonal Antibody

 Also Known As   

Lipase Monoclonal Antibody

 Product Synonym Names    Anti-Lipase; Lipase
 Product Gene Name   

anti-PNLIP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 10; NC_000010.10 (118305428..118327367). Location: 10q26.1
 OMIM    246600
 3D Structure    ModBase 3D Structure for P16233
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 Clonality    Monoclonal
 Isotype    IgG1
 Host    Mouse
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 Specificity    Anti-Lipase [Human pancreatic lipase (4 clones). LP]
These antibodies specifically recognize pancreatic lipase.
 Form/Format    1 ml ascites or 1 mg Protein G-purified antibody in PBS, pH 7.4
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 Antigen    Purified human pancreatic lipase.
 Activity    Ig mg/ml* :35.9
ELISA Titer**:1:102,400
(Note: * Determined by radial immunodiffusion for several lots of ascites.
**ELISA is an indirect assay against pancreatic lipase on the solid phase. Titers represent endpoint dilutions that achieve absorbance values >= 0.1)
 Stabilizer    None
 Preservatives    None. Available on request
 Dilutions Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of anti-PNLIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-PNLIP antibody    Enzyme and Enzyme Inhibitor Antibodies
 Applications Tested/Suitable for anti-PNLIP antibody   

Immunoassay

 Application Notes for anti-PNLIP antibody    These antibodies may be used in immunoassays to detect and quantitate pancreatic lipase. Other applications are under investigation.
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NCBI/Uniprot data below describe general gene information for PNLIP. It may not necessarily be applicable to this product.
 NCBI GI #    190140
 NCBI GeneID    5406
 NCBI Accession #    AAA60129.1 [Other Products]
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 UniProt Primary Accession #    P16233 [Other Products]
 UniProt Secondary Accession #    Q5VSQ2 [Other Products]
 UniProt Related Accession #    P16233 [Other Products]
 Molecular Weight    51,157 Da [Similar Products]
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 NCBI Official Full Name    lipase
 NCBI Official Synonym Full Names    pancreatic lipase
 NCBI Official Symbol    PNLIP [Similar Products]
 NCBI Official Synonym Symbols   
PL; PTL
[Similar Products]
 NCBI Protein Information    pancreatic triacylglycerol lipase; OTTHUMP00000020564; triacylglycerol acylhydrolase
 UniProt Protein Name    Pancreatic triacylglycerol lipase
 Protein Family    Lipase
 UniProt Gene Name    PNLIP [Similar Products]
 UniProt Entry Name    LIPP_HUMAN
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 NCBI Summary for PNLIP    This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq]
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 UniProt Comments for PNLIP    PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]

Protein type: Secreted; Hydrolase; Lipid Metabolism - glycerolipid; EC 3.1.1.3; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q26.1

Cellular Component: extracellular region

Molecular Function: triacylglycerol lipase activity; metal ion binding

Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid digestion; lipid catabolic process

Disease: Pancreatic Lipase Deficiency
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 Research Articles on PNLIP    1. Combination of two mutations with a promising one at the entrance of the catalytic cavity (K80E) negatively affected the lipase activity at neutral pH but not that at acidic pH.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PNLIP antibodyPathways associated with anti-PNLIP antibody
 Reference Product  PubMed Publications
 CLPS antibody  >2 publications with PNLIP and CLPS
 Products by Pathway  Pathway Diagram
 Digestion Of Dietary Lipid Pathway antibodies  Digestion Of Dietary Lipid Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Steroid Hormones And Vitamins A And D Pathway antibodies  Metabolism Of Steroid Hormones And Vitamins A And D Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
Diseases associated with anti-PNLIP antibodyOrgans/Tissues associated with anti-PNLIP antibody
 Disease Name  Pubmed Publications
 Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules Antibodies  >2426 publications with PNLIP and Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules
 Pancreatitis Antibodies  >9 publications with PNLIP and Pancreatitis
 Obesity Antibodies  >5 publications with PNLIP and Obesity
 Insulin Resistance Antibodies  >2 publications with PNLIP and Insulin Resistance
 Neoplasms Antibodies  >2 publications with PNLIP and Neoplasms
 Diabetes Complications Antibodies  >1 publications with PNLIP and Diabetes Complications
 Hypertriglyceridemia Antibodies  >1 publications with PNLIP and Hypertriglyceridemia
 Colonic Neoplasms Antibodies  >1 publications with PNLIP and Colonic Neoplasms
 Heart Failure Antibodies  >1 publications with PNLIP and Heart Failure
 Atherosclerosis Antibodies  >1 publications with PNLIP and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >15 publications with PNLIP and Pancreas
 Liver Antibodies  >2 publications with PNLIP and Liver
 Heart Antibodies  >1 publications with PNLIP and Heart
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