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anti-Ly6c1 antibody :: Rat anti-Mouse Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS605460 anti-Ly6c1 antibody
Unit / Price
0.1 mg  /  $690 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly6c1), Monoclonal Antibody

 Also Known As   

Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly-6c)

 Product Synonym Names    Anti -Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly-6c)
 Product Gene Name   

anti-Ly6c1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 15; NC_000081.5 (74875443..74879260, complement). Location: 15 D3; 15 42.7 cM
 3D Structure    ModBase 3D Structure for P09568
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 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    9G221
 Host    Rat
 Species Reactivity    Mouse
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 Specificity    Recognizes mouse macrophage precursor cells in the mid-stage of their development (late CFU-M, monoblasts and monocytes).
 Purity/Purification    Affinity Purified
Purified
 Form/Format    Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
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 Immunogen    Mouse macrophage cell lines
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-Ly6c1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Ly6c1 antibody

   The antigen is a 14kD surface protein which is very similar to Ly-6C and may be analogous to human CD59. It is inducible by IFN-alpha, IFN-beta and IFN-gamma. In tissue sections, the antigen is found on macrophage precursor subpopulations. In the bone marrow and hemopoietic islands of the lymphoid organs, and in the spleen. Activated macrophages in inflammatory tissues also express the related antigen. The monoclonal antibody also identifies activated macrophages in inflammatory tissues where the simultaneous use of the murine pan-macrophage marker BM8 (anti-F4/80) is recommended. In combination with an anti-mouse CD31/PECAM-1 antibody, can be used to evaluate the cellular composition in murine bone marrow (e.g. using flow cytometric analysis). Also detects a wide range of endothelial cells.
 Product Categories/Family for anti-Ly6c1 antibody    Antibodies; Abs to Cell Surface Proteins
 Applications Tested/Suitable for anti-Ly6c1 antibody   

Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

 Application Notes for anti-Ly6c1 antibody    Suitable for use in Flow Cytometry and Immunohistochemistry.
Dilution: Flow Cytometry: 1:50
Immunohistochemistry: 1:50
The antigen is glutaraldehyde (0.05%) and paraformaldehyde (1%) resistant.
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NCBI/Uniprot data below describe general gene information for Ly6c1. It may not necessarily be applicable to this product.
 NCBI GI #    58331142
 NCBI GeneID    17067
 NCBI Accession #    NP_034871.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_010741.2 [Other Products]
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 UniProt Primary Accession #    P09568 [Other Products]
 UniProt Secondary Accession #    P09568; Q58E40; Q8C2D8; Q91XG0 [Other Products]
 UniProt Related Accession #    P0CW02; P0CW03 [Other Products]
 Molecular Weight    14,193 Da [Similar Products]
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 NCBI Official Full Name    lymphocyte antigen 6C2
 NCBI Official Synonym Full Names    lymphocyte antigen 6 complex, locus C1
 NCBI Official Symbol    Ly6c1 [Similar Products]
 NCBI Official Synonym Symbols   
Ly6c; Ly-6C; Ly6c2; Ly-6C1; AA682074; AA959465
[Similar Products]
 NCBI Protein Information    lymphocyte antigen 6C2; ly-6C2; Lymphocyte antigen Ly-6C; lymphocyte antigen 6 complex, locus C
 UniProt Protein Name    Lymphocyte antigen 6C1
 Protein Family    Lymphocyte antigen
 UniProt Gene Name    Ly6c1 [Similar Products]
 UniProt Synonym Gene Names    Ly6c [Similar Products]
 UniProt Entry Name    LY6C1_MOUSE
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 UniProt Comments for Ly6c1    LY6C1:

Cellular Component: membrane; plasma membrane; external side of plasma membrane
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 Research Articles on Ly6c1    1. TNF-alpha-dependent regulation of acute pancreatitis severity by Ly-6C(hi) monocytes in mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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