NP_057670.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,153 Da
NCBI Official Full Name
Homo sapiens MAP3K12 binding inhibitory protein 1 (MBIP), transcript variant 1, mRNA
NCBI Official Synonym Full Names
MAP3K12 binding inhibitory protein 1
NCBI Protein Information
MAP3K12-binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein
UniProt Protein Name
MAP3K12-binding inhibitory protein 1
UniProt Synonym Protein Names
MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein
UniProt Entry Name
MBIP1_HUMAN
UniProt Comments for MBIP
MBIP: Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 14q13.3
Cellular Component: cytoplasm; nucleolus; nucleus
Molecular Function: identical protein binding; protein binding; protein kinase inhibitor activity
Biological Process: establishment and/or maintenance of chromatin architecture; inactivation of MAPK activity during osmolarity sensing
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Products associated with anti-MBIP antibody
Pathways associated with anti-MBIP antibody
Diseases associated with anti-MBIP antibody
Organs/Tissues associated with anti-MBIP antibody
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