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anti-MEIS2 antibody :: Mouse anti-Human MEIS2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120433
Quality Control
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MEIS2, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human MEIS2

 Product Synonym Names    Homo sapiens Meis homeobox 2, mRNA (cDNA clone MGC:54158 IMAGE:6066728), complete cds.; MRG1; HsT18361
 Product Gene Name   

anti-MEIS2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601740
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    425C2a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-MEIS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MEIS2 antibody

   This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.[NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-MEIS2 antibody   

Dot Blot (DB)

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 Quality Control of anti-MEIS2 antibody    Left: Western blot analysis of immunized recombinant protein, using anti-MEIS2 monoclonal antibody.
anti-MEIS2 antibody Quality Control image
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NCBI/Uniprot data below describe general gene information for MEIS2. It may not necessarily be applicable to this product.
 NCBI GI #    29791509
 NCBI GeneID    4212
 NCBI Accession #    BC050431 [Other Products]
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 UniProt Secondary Accession #    Q96DI2; Q96KI4; Q96KI5; Q9NRS1; Q9NRS2; Q9NRS3; A6NJI5; A8MWD5; B3KP98; B3KPQ6 [Other Products]
 UniProt Related Accession #    O14770 [Other Products]
 Molecular Weight    42,272 Da
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 NCBI Official Full Name    Homo sapiens Meis homeobox 2, mRNA
 NCBI Official Synonym Full Names    Meis homeobox 2
 NCBI Official Symbol    MEIS2 [Similar Products]
 NCBI Official Synonym Symbols   
MRG1; HsT18361
[Similar Products]
 NCBI Protein Information    homeobox protein Meis2; Meis homolog 2; Meis1, myeloid ecotropic viral integration site 1 homolog 2; Meis1-related gene 1; TALE homeobox protein Meis2; meis1-related protein 1
 UniProt Protein Name    Homeobox protein Meis2
 UniProt Synonym Protein Names   
Meis1-related protein 1
 Protein Family    Homeobox protein
 UniProt Gene Name    MEIS2 [Similar Products]
 UniProt Entry Name    MEIS2_HUMAN
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 NCBI Summary for MEIS2    This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MEIS2    MEIS2: a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription cofactor activity; transcription factor activity; transcription factor binding; transcription corepressor activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of myeloid cell differentiation; eye development; response to mechanical stimulus; pancreas development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
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 Research Articles on MEIS2    1. The data suggest existence of a complex regulatory pathway in the trabecular meshwork part of which includes interactions between FOXC1, miR-204, MEIS2, and ITGbeta1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MEIS2 antibodyDiseases associated with anti-MEIS2 antibody
 Reference Product  PubMed Publications
 PBX1 antibody  >16 publications with MEIS2 and PBX1
 PAX6 antibody  >13 publications with MEIS2 and PAX6
 PBX3 antibody  >6 publications with MEIS2 and PBX3
 HOXA9 antibody  >4 publications with MEIS2 and HOXA9
 HOXB7 antibody  >1 publications with MEIS2 and HOXB7
 SP1 antibody  >1 publications with MEIS2 and SP1
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with MEIS2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >2 publications with MEIS2 and Disease Models, Animal
 Lung Diseases Antibodies  >2 publications with MEIS2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >2 publications with MEIS2 and Cardiovascular Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with MEIS2 and Neurobehavioral Manifestations
 Heart Defects, Congenital Antibodies  >2 publications with MEIS2 and Heart Defects, Congenital
 Lung Neoplasms Antibodies  >2 publications with MEIS2 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with MEIS2 and Neoplasms, Experimental
 Prostatic Neoplasms Antibodies  >1 publications with MEIS2 and Prostatic Neoplasms
 Kidney Diseases Antibodies  >1 publications with MEIS2 and Kidney Diseases
Organs/Tissues associated with anti-MEIS2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >41 publications with MEIS2 and Brain
 Eye Antibodies  >13 publications with MEIS2 and Eye
 Embryonic Tissue Antibodies  >13 publications with MEIS2 and Embryonic Tissue
 Heart Antibodies  >9 publications with MEIS2 and Heart
 Pancreas Antibodies  >6 publications with MEIS2 and Pancreas
 Bone Antibodies  >4 publications with MEIS2 and Bone
 Muscle Antibodies  >3 publications with MEIS2 and Muscle
 Vascular Antibodies  >3 publications with MEIS2 and Vascular
 Placenta Antibodies  >3 publications with MEIS2 and Placenta
 Lung Antibodies  >2 publications with MEIS2 and Lung
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